Competitive cocrystallization and its application in the separation of flavonoids
IUCrJ, 2021 Recently, cocrystallization has been widely employed to tailor physicochemical properties of drugs in the pharmaceutical field. In this study, cocrystallization was applied to separate natural compounds with similar structures.
Yanming Xia +5 more
doaj +1 more source
Intermolecular interactions in optical cavities: An ab initio QED study [PDF]
, 2021 Intermolecular bonds are weak compared to covalent bonds, but they are strong enough to influence the properties of large molecular systems. In this work, we investigate how strong light–matter coupling inside an optical cavity can modify intermolecular ...
Tor S. Haugland +9 more
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Quantitative analysis of intermolecular interactions in orthorhombic rubrene
IUCrJ, 2015 Rubrene is one of the most studied organic semiconductors to date due to its high charge carrier mobility which makes it a potentially applicable compound in modern electronic devices.
Venkatesha R. Hathwar +8 more
doaj +1 more source
Fingerprinting intermolecular interactions in molecular crystals
, 2009 We have recently described a remarkable new way of exploring packing modes and intermolecular interactions in molecular crystals using a novel partitioning of crystal space.
McKinnon, Joshua, Spackman, Mark Arthur
core +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Investigating Intermolecular Interactions in Multi-Component Pharmaceuticals [PDF]
For many years, the question of how to improve the physical properties of Active Pharmaceutical Ingredients (APIs) without changing their covalent structure has challenged the pharmaceutical industry.
Adjimani, Joseph Tettey
core +4 more sources
van der Waals Potential: An Important Complement to Molecular Electrostatic Potential in Studying Intermolecular Interactions [PDF]
, 2020 Electrostatic and van der Waals (vdW) interactions are two major components of intermolecular weak interactions. Electrostatic potential has been a very popular function in revealing electrostatic interaction between the system under study and other ...
Tian, Lu, Qinxue, Chen
core +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Polarization Dependence of Low-Frequency Vibrations from Multiple Faces in an Organic Single Crystal
Crystals, 2019 Recent developments in optical filters have enabled the facile use of Raman spectroscopy for detection of low frequency (LF) vibrational modes. LF-Raman spectroscopy offers fast and sensitive characterization of LF vibrations, and enables the measurement
Irena Nemtsov +3 more
doaj +1 more source