The intermolecular interactions of the four selected drugs and letrozole with aromatase enzyme.
, 2023 The intermolecular interactions of the four selected drugs and letrozole with aromatase enzyme.
Walaa Ibraheem +7 more
core +1 more source
The intermolecular interactions of the shortlisted drugs and abemaciclib with CDK4.
, 2023 The intermolecular interactions of the shortlisted drugs and abemaciclib with CDK4.
Abdulrahim A. Alzain (12938296) +3 more
core +1 more source
The Intermolecular Interactions of Pyrene and its Oxides in Toluene Solution [PDF]
, 2022 In this work, the Conformer-Rotamer Ensemble Sampling Tool, (CREST) with the underlying semi-empirical GFN2-xtb method was used for automated geometry exploration of the homodimers of pyrene, pyrene-4,5-dione, and pyrene-4,5,9,10- tetraone, along with ...
Alex, Brown +3 more
core +2 more sources
Competitive cocrystallization and its application in the separation of flavonoids
IUCrJ, 2021 Recently, cocrystallization has been widely employed to tailor physicochemical properties of drugs in the pharmaceutical field. In this study, cocrystallization was applied to separate natural compounds with similar structures.
Yanming Xia +5 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Quantitative analysis of intermolecular interactions in orthorhombic rubrene
IUCrJ, 2015 Rubrene is one of the most studied organic semiconductors to date due to its high charge carrier mobility which makes it a potentially applicable compound in modern electronic devices.
Venkatesha R. Hathwar +8 more
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
Intermolecular Sulfur···Oxygen Interactions: Theoretical and Statistical Investigations
, 2015 Intermolecular S···O interactions are very common and are important in biological systems, but until recently, the presence of these contacts in protein–ligand systems largely depended on serendipitous discovery instead of rational design.
Xuejin Zhang (576456) +3 more
core +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Polarization Dependence of Low-Frequency Vibrations from Multiple Faces in an Organic Single Crystal
Crystals, 2019 Recent developments in optical filters have enabled the facile use of Raman spectroscopy for detection of low frequency (LF) vibrational modes. LF-Raman spectroscopy offers fast and sensitive characterization of LF vibrations, and enables the measurement
Irena Nemtsov +3 more
doaj +1 more source