Results 91 to 100 of about 7,451,303 (266)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Internal Audit Activities and Plans [PDF]
, 2016 This information package includes reports submitted by the WSU Office of Internal Audit to the Kansas Board of Regents Fiscal Affairs and Audit ...
Office of Internal Audit
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
UNHCR’s role in IDP protection: opportunities and challenges [PDF]
Forced Migration Review, 2006 Roberta Cohen has encouraged, cajoled and even shamedthe UN into assuming a more effective role to protect IDPs.Throughout two decades of tireless advocacy she hasconsistently argued that UNHCR should be more engagedin IDP protection.
Erika Feller
doaj
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Implementing the UNESCO Convention in EU's Internal Policies [PDF]
, 2010 This briefing note was prepared by invitation from the European Parliament's Committee on Culture and Education. It provides an analysis of how the existent EU internal policies reflect the spirit and the letter of the UNESCO Convention on Cultural ...
Burri, Mira
core +2 more sources
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Internal migration in India: distress and opportunities, a study of internal migrants to vulnerable occupations in Delhi [PDF]
, 2010 "Centre for Equity Studies undertook a study to investigate the lived experiences of internal migrants to vulnerable occupations to Delhi, one of the most powerful magnets for such migration in the country.
Mander, Harsh, Sahgal, Gayatri
core +1 more source
Regional or national protection for Great Lakes IDPs? [PDF]
Forced Migration Review, 2006 Roberta and I differ on both substantive issues andmethodological approaches to the protection ofIDPs. The key problem facing IDPs in Africa’s GreatLakes is not lack of regional mechanisms but theabsence of strong national protection systems.
Zachary A Lomo
doaj
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source