Results 91 to 100 of about 12,238,800 (263)
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda +12 more
wiley +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Achievements and limitations of the Guiding Principles in Burma [PDF]
Forced Migration Review, 2008 While the Guiding Principles have galvanised awarenessof and assistance for IDPs in Burma, they have been anineffective tool for dealing with a predatory military junta.
Thailand Burma Border Consortium
doaj
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
A road map to the end of displacement in Sri Lanka? [PDF]
Forced Migration Review, 2006 The Consortium of Humanitarian Agencies (CHA) is anon-profit agency representing those working in thehumanitarian sector in Sri Lanka. Our work on internaldisplacement, the knowledge we have gained and thecapacity we have developed owe much to ...
Jeevan Thiagarajah
doaj
FEBS Open Bio, EarlyView.ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui +10 more
wiley +1 more source
The Effect of L1 Linguistic and Cultural Background on L2 Pragmatic Competence
LanguagesThis study examined the pragmatic competence and awareness of L2 learners of English, with a focus on their request strategies in L2 English, levels of (in)directness, request perspective, internal and external modifications, and the impact of tasks. The
Sviatlana Karpava
doaj +1 more source
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Ensuring the growth of the country’s economy
Путеводитель предпринимателяThe article examines and analyzes the problems and issues of the dynamics of the country’s economy (GDP) under the influence of external and internal factors and conditions in the second half of the year and in general for 2023. The dynamics of inflation
L. A. Akhmetov, M. A. Bulavina
doaj +1 more source