Results 31 to 40 of about 2,365,141 (284)

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

16th century Persian tiles in dialogue with 21st century digital tiles in the Sadrian universe [PDF]

open access: yes, 2016
This article brings together tiles of 16th century Persian architecture and 21st century digital tiles of moving image to explore new potentials beyond the perceived image.
Emadi, Azadeh
core  

El capital social como enfoque teórico en Dirección Estratégica [PDF]

open access: yes, 2019
[EN] The objective of this research paper is to investigate, from a theoretical point of view, the strategic relevance of social capital. In recent years, academic literature in this field has witnessed remarkable growth, recognizing social capital as a ...
Donate Manzanares, Mario Javier   +2 more
core   +4 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Socio-Cultural Aspects of Present-Day Internal Suburban Migration in Slovakia – in the Example of the Village Soblahov in the Trenčín District

open access: yesSlovenský Národopis, 2019
The present-day internal migration of people from larger or smaller towns to the countryside is characterised by suburbanisation tendencies that considerably transform the socio-cultural and spatial structure of suburban municipalities.
Bošelová Miriama
doaj   +1 more source

Predicting the value of product service-systems for potential future implementers: results from multiple industrial case studies [PDF]

open access: yes, 2017
The great impact played by Product/Service-Systems (PSS) on industry and academia can be motivated by the need for modernizing business models, carrying out internal companies' reconfiguration, enhancing environmental sustainability.
Annarelli, Alessandro   +3 more
core   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

ENDOMARKETING EM INSTITUIÇÕES DE ENSINO SUPERIOR: UM ESTUDO NA UNIVERSIDADE FEDERAL DO PAMPA

open access: yesRevista Gestão Universitária na América Latina, 2018
The importance of actions aimed at satisfying the demands of internal clients of organizations is increasingly evident in view of the need to develop a pleasant working environment for workers.
Mikaela Daiane Prestes Floriano   +1 more
doaj   +1 more source

Internal or External Grounds for the Nontransitivity of “Better/Worse than” [PDF]

open access: yes, 2014
In his book Rethinking the Good: Moral Ideals and the Nature of PracticalReasoning Larry Temkin contrasts two views of ideals for evaluating outcomes:the Internal Aspects View and the Essentially Comparative View.
Persson, Ingmar
core  

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