Results 41 to 50 of about 2,822,028 (303)
Financial conditions in recent years have provided developing countries with unprecedentedopportunities to tap international bond markets, increasing access to commercial debtfinancing. On that background, developing countries are broadening the range of debtinstruments employed in implementing debt management strategies, and this has changed therisk ...
van der Wansem, Patrick B. G. +2 more
openaire +2 more sources
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
We investigated the effect of adding nano-wollastonite on the physical, mechanical and morphological properties of gypsum Composites. The ratio percentage of bagasse mixing as lignocellulosic material with gypsum at three levels (85:15; 75:25; 65:35 ...
Ali Hassanpoor Tichi +2 more
doaj
The Investigation of Physical and Mechanical Properties of Oriented Strand Board (OSB) Production Using Corn Stalks Residues [PDF]
: The application of corn stalks in the production of oriented strand board (OSB) is investigated. Corn stalks strands were produced in three sizes of 50, 75 and 100 millimeters length and dried to reach 2% moisture content.
Abolfazl Kargarfard
doaj +1 more source
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
International Bond Risk Premia [PDF]
We identify local and global factors across international bond markets that are poorly spanned by the cross-section of yields but have strong forecasting power for future bond excess returns. Local and global factors are jointly signicant predictors of bond returns, where the global factor is closely linked to US bond risk premia and international ...
Dahlquist, Magnus, Hasseltoft, Henrik
openaire +3 more sources
Temporary wafer bonding by polyelectrolyte interlayers
S.179-186Polyelectrolyte multilayers of just a few nanometers thickness were used for direct bonding of silicon, thermally oxidized silicon, and borosilicate wafers, respectively, and the bonded wafer pairs were characterized during and after annealing ...
Klages, C.-P. +4 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source

