Benchmarking Treatment Response in Tourette’s Disorder: A Psychometric Evaluation and Signal Detection Analysis of the Parent Tic Questionnaire [PDF]
, 2018 This study assessed the psychometric properties of a parent-reported tic severity measure, the Parent Tic Questionnaire (PTQ), and used the scale to establish guidelines for delineating clinically significant tic treatment response. Participants were 126
Peterson, Alan L. +7 more
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
MedicinaBackground and Objective: Musculoskeletal disorders affect a large portion of the population worldwide. The musculoskeletal health questionnaire is a helpful tool for assessing the health state of patients with these disorders.
Giovanni Galeoto +6 more
doaj +1 more source
Validation of the Spanish Language Version of the Learning and Performance Orientations in Physical Education Classes Questionnaire. (Validación de la versión Española del Cuestionario de Orientaciones al Aprendizaje y el Rendimiento en las clases de Educación Física). [PDF]
Revista Internacional de Ciencias del Deporte, 2010 The objective of this study was to examine the factorial validity and reliability of the Learning and Performance Orientations in Physical Education Classes Questionnaire (LAPOPECQ) with adolescent Spanish physical education students.
Eduardo M. Cervelló Gimeno +3 more
doaj
, 2014 CONTEXT. The ESO archive of FORS1 spectropolarimetric observations may be used to create a homogeneous database of magnetic field measurements. However, no systematic comparison of FORS field measurements to those obtained with other instruments has been
Bagnulo, S. +2 more
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
, 2014 The consistency formula for set theory can be stated in terms of the free-variables theory of primitive recursive maps. Free-variable p. r. predicates are decidable by set theory, main result here, built on recursive evaluation of p. r.
Pfender, Michael
core
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Internal consistency, convergent validity, and structural validity of the Japanese version of the Physical Activity Self-Regulation scale (PASR-12) among Japanese workers: A validation study [PDF]
, 2016 Kazuhiro Watanabe +4 more
openalex +1 more source