Results 71 to 80 of about 490,640 (262)

Dataset on the Validation and Standardization of the Questionnaire for the Self-Assessment of Service-Learning Experiences in Higher Education (QaSLu)

Data
This dataset shows the original validation and standardization of the Questionnaire for the Self-Assessment of Service-Learning Experiences in Higher Education (QaSLu).
Roberto Sánchez-Cabrero, Elena López-de-Arana Prado, Pilar Aramburuzabala, Rosario Cerrillo   +3 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Vagus Nerve Stimulation-Induced Laryngeal Motor Evoked Potentials: A Possible Biomarker of Effective Nerve Activation

Frontiers in Neuroscience, 2019
Vagus nerve stimulation (VNS) therapy is associated with laryngeal muscle activation and induces voice modifications, well-known side effects of the therapy resulting from co-activation of the recurrent laryngeal nerve. In this study, we describe the non-
Simone Vespa, Lars Stumpp, Charlotte Bouckaert, Jean Delbeke, Hugo Smets, Joaquin Cury, Susana Ferrao Santos, Susana Ferrao Santos, Herbert Rooijakkers, Antoine Nonclercq, Robrecht Raedt, Kristl Vonck, Kristl Vonck, Riëm El Tahry, Riëm El Tahry   +14 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Turkish version of the Tilburg Frailty Indicator

Clinical Interventions in Aging, 2019
Yildiray Topcu, Fatih Tufan, Cihan Kilic Department of Geriatrics, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey Background: Recently frailty has drawn significant interest as an important predictor of several clinically relevant ...
Topcu Y, Tufan F, Kilic C
doaj  

Thinking Styles Inventory: Psychometric features in college students from Buenos Aires

Interacciones, 2019
Background: Thinking styles lead to describe how people use their abilities when they have to deal with problem solving situations. The Thinking Styles Inventory –TSI- is one of the most worldwide employed scales, developed to assess 13 thinking styles ...
Agustín Freiberg Hoffmann, Fabiana Uriel , Rocío Fernández Da Lama, Mercedes Fernández Liporace   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Análisis factorial confirmatorio del inventario multicultural de la expresión de la ira y hostilidad [PDF]

Liberabit, 2016
El propósito principal del presente estudio fue verificar la estructura factorial de las dos escalas que componen el Inventario Multicultural de la Expresión de la Ira y Hostilidad desde una perspectiva confirmatoria.
Manolete S. Moscoso, César Merino-Soto, Sergio Dominguez-Lara, Cecilia B. Chau, Mary Claux   +4 more
doaj  

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source