Results 71 to 80 of about 484,814 (261)

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Vagus Nerve Stimulation-Induced Laryngeal Motor Evoked Potentials: A Possible Biomarker of Effective Nerve Activation

Frontiers in Neuroscience, 2019
Vagus nerve stimulation (VNS) therapy is associated with laryngeal muscle activation and induces voice modifications, well-known side effects of the therapy resulting from co-activation of the recurrent laryngeal nerve. In this study, we describe the non-
Simone Vespa, Lars Stumpp, Charlotte Bouckaert, Jean Delbeke, Hugo Smets, Joaquin Cury, Susana Ferrao Santos, Susana Ferrao Santos, Herbert Rooijakkers, Antoine Nonclercq, Robrecht Raedt, Kristl Vonck, Kristl Vonck, Riëm El Tahry, Riëm El Tahry   +14 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Dataset on the Validation and Standardization of the Questionnaire for the Self-Assessment of Service-Learning Experiences in Higher Education (QaSLu)

Data
This dataset shows the original validation and standardization of the Questionnaire for the Self-Assessment of Service-Learning Experiences in Higher Education (QaSLu).
Roberto Sánchez-Cabrero, Elena López-de-Arana Prado, Pilar Aramburuzabala, Rosario Cerrillo   +3 more
doaj   +1 more source

Thinking Styles Inventory: Psychometric features in college students from Buenos Aires

Interacciones, 2019
Background: Thinking styles lead to describe how people use their abilities when they have to deal with problem solving situations. The Thinking Styles Inventory –TSI- is one of the most worldwide employed scales, developed to assess 13 thinking styles ...
Agustín Freiberg Hoffmann, Fabiana Uriel , Rocío Fernández Da Lama, Mercedes Fernández Liporace   +3 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Turkish version of the Tilburg Frailty Indicator

Clinical Interventions in Aging, 2019
Yildiray Topcu, Fatih Tufan, Cihan Kilic Department of Geriatrics, Istanbul School of Medicine, Istanbul University, Istanbul, Turkey Background: Recently frailty has drawn significant interest as an important predictor of several clinically relevant ...
Topcu Y, Tufan F, Kilic C
doaj  

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source