Results 81 to 90 of about 484,814 (261)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Moderators of the internal consistency of error‐related negativity scores: A meta‐analysis of internal consistency estimates

Psychophysiology, 2019
Abstract To ensure adequate reliability (i.e., internal consistency), it is common in studies using event‐related brain potentials (ERPs) to exclude participants for having too few trials. This practice is particularly relevant for error‐related ERPs, such as error‐related negativity (ERN), where the number of ...
openaire   +5 more sources

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

A primer on reliability testing of a rating scale

Indian Journal of Psychiatry
In this article, the second of a series on rating scale translation, adaptation, and psychometric testing, we focus on reliability testing of a rating scale.
Vikas Menon, Sandeep Grover, Snehil Gupta, PV Indu, Deenu Chacko, K Vidhukumar   +5 more
doaj   +1 more source

The Internal Consistency of Arithmetic with Infinite Descent [PDF]

, 2002
Summary: The consistency of arithmetic is shown without the recourse of transfinite induction or the detour of an infinite set. Arithmetic without an induction postulate, but with infinite descent, is Fermat Arithmetic coupled with Kronecker's ``general arithmetic'' of indeterminates. Fermat arithmetic is self-consistent or self-contained.
openaire   +3 more sources

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Evaluation of the Psychometric Properties of the Musculoskeletal Health Questionnaire (MSK-HQ) in a Population of Professional Basketball Players: A Cross-Sectional Study

Medicina
Background and Objective: Musculoskeletal disorders affect a large portion of the population worldwide. The musculoskeletal health questionnaire is a helpful tool for assessing the health state of patients with these disorders.
Giovanni Galeoto, Kennet Matteo Viglianisi, Anna Berardi, Giovanni Sellitto, Ilaria Ruotolo, Rachele Simeon, Alessandra Carlizza   +6 more
doaj   +1 more source

Validation of the Spanish Language Version of the Learning and Performance Orientations in Physical Education Classes Questionnaire. (Validación de la versión Española del Cuestionario de Orientaciones al Aprendizaje y el Rendimiento en las clases de Educación Física). [PDF]

Revista Internacional de Ciencias del Deporte, 2010
The objective of this study was to examine the factorial validity and reliability of the Learning and Performance Orientations in Physical Education Classes Questionnaire (LAPOPECQ) with adolescent Spanish physical education students.
Eduardo M. Cervelló Gimeno, Ruth Jiménez Castuera, Manuel Moya Ramón, Juan Antonio Moreno Murcia   +3 more
doaj