Results 151 to 160 of about 15,663,687 (311)

Texas Lottery Commission Internal Audit: Follow-Up Review

open access: yes, 2012
Report detailing the Internal Audit Division's follow-up review of six previously conducted internal audits in order to determine whether management has taken actions to correct conditions noted in the prior audits or has accepted the risk of not taking ...
Texas Lottery Commission. Internal Audit Division.
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Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

open access: yesFEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto   +14 more
wiley   +1 more source

A novel sensitive hexaplex high-resolution melt assay for identification of five human Plasmodium species plus internal control. [PDF]

open access: yesActa Trop, 2023
Srisutham S   +7 more
europepmc   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

Beta1 subunits enable fentanyl‐induced BK channel activation and opioid regulation of cerebral artery diameter

open access: yesFEBS Open Bio, EarlyView.
During the current opioid crisis, the majority of overdose deaths are attributed to ultra‐potent synthetic opioids, such as fentanyl. While fentanyl exerts its action via opioid receptors, we propose that potassium channels in the brain blood vessels may also sense fentanyl.
Shiwani Thapa   +4 more
wiley   +1 more source

From Internal Auditing to Enterprise Risk Management : the Case of the Telecomitalia Group

open access: yes, 2007
Ana analysis of Internal Control Systems in large ...
S. BOZZOLAN, BERETTA, SERGIO
core  

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

open access: yesFEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

Minutes of the Trustees Internal Improvement Fund of the State of Florida.

open access: yes, 1906
Includes also Financial statement.Includes also Financial statement.Mode of access: Internet.Published under authority of Trustees.Continued by: Florida. Trustees of Internal Improvement Fund.
Florida. Trustees of Internal Improvement Fund.
core  

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