Results 61 to 70 of about 2,082,908 (266)
THE INTERNAL CONTROL MODELS IN ROMANIA [PDF]
Internal control is indissolubly linked to business and accounting. Throughout history, domestic and international trade has grown exponentially, which has led to an increasing complexity of internal control, to new methods and techniques to control ...
TEODORESCU CRISTIAN DRAGOȘ
doaj
Boards of directors have the ultimate responsibility for governance – including internal control – in their organisations. Management is tasked with the design, implementation and maintenance of internal control systems. Internal auditors play a key role
Houdini Fourie, Christo Ackermann
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Internal financial control and internal audit in budget institutions
It is an undeniable fact that the need for continuous improvement in internal auditing and internal financial controls in budgetary institutions is due to the continuous transformation of the Russian Federation's budget model, which requires rational and
I. J. Saifutdinov
doaj
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
ERANAN PENGENDALIAN INTERNAL PADA KOPERASI PURLINA KOTA SEMARANG
Tujuan penelitian ini untuk menelaah bagaimana peranan pengendalian internal dalam lingkungan, penilaian risiko, aktivitas pengendalian, informasi dan komunikasi, monitoring/pemantauan di Koperasi Purlina Kota Semarang.
Rizky Widya Astari, Ade Rustiana
doaj
Theoretical grounds of internal audit in the system of state financial control in Ukraine [PDF]
The article considers modern directions of reformation of the system of state financial control connected with introduction of the state internal financial control.
Dikan Larysa V., Kalinkin Dmytro V.
doaj
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source

