Results 71 to 80 of about 13,572,866 (311)

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Current Situation and Issues of Internal Control System in China

open access: yes, 2018
In China, many accounting frauds such as window-dressing occur, and both means and amount of fraud has become wider and bigger. To cope with the accounting frauds, the Chinese government and accounting professional institution have been setting laws or ...
徐, 陽
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

INTERNAL CONTROL ACTIVITIES: CAUSE AND EFFECT OF A GOOD GOVERNANCE OF ACCOUNTING REPORTINGS AND FISCAL DECLARATIONS [PDF]

open access: yes
As a subsystem of the management system, the internal control could beviewed as the primordial condition for the efficient and effective accomplishment of thegeneral and specific objectives of any organization.
Mihaela Prozan   +2 more
core  

Dimensi Internal Control dan Internal Auditor dalam Acoountability dan Fraud Prevention [PDF]

open access: yes, 2012
KARTINI. Dimensi Internal Control dan Internal Auditor dalam Acoountability dan Fraud Prevention, (dibimbing oleh Basri Hasanuddin sebagai promotor, Gagaring Pagalung dan Darwis Said sebagai ko-promotor)\ud \ud Penelitian ini bertujuan untuk mengetahui ...
Kartini
core  

THEORETICAL AND METHODOLOGICAL BASIS OF THE STUDY OF ENVIRONMENTAL AUDIT IN KAZAKHSTAN

open access: yesВісник Київського національного університету імені Тараса Шевченка. Серія Економіка, 2014
Practical problems of modern economic development of the country are associated with unresolved major theoretical issues in the field of auditing. One of them, in our opinion, is to determine the status of the audit as a form of scientific knowledge ...
V. Berezuyuk
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Investigating the Impact of Earnings Management and Internal Control on the Financial Performance of Banks Using a Spatial Artificial Intelligence Approach [PDF]

open access: yesInternational Journal of Management, Accounting and Economics
This study examines the relationship between earnings management and financial performance of banks listed on the stock exchanges in Iran and Iraq, focusing on the role of internal controls. This study utilizes the statistical population of 44 banks from
Wisam Fadhil Hanoon   +2 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

TÜRKİYE’DEKİ BÜYÜKŞEHİR BELEDİYELERİNİN İÇ KONTROL SİSTEMLERİNİN KAMU İÇ KONTROL STANDARTLARINA UYUM DURUMLARININ ARAŞTIRILMASI - THE RESEARCH OF COMPLIANCE STATUS OFMETROPOLITAN MUNICIPALITIES’INTERNAL CONTROL SYSTEMS IN TURKEY TO THE PUBLIC INTERNAL CONTROL STANDARDS

open access: yesMehmet Akif Ersoy Üniversitesi Sosyal Bilimler Enstitüsü Dergisi, 2019
İç kontrol sistemi, kurumların amaçları doğrultusunda belirledikleri hedeflere ulaşmalarına engel olabilecek riskleri en aza indirerek kurum yönetimine; mevzuata uygun etkili, ekonomik ve verimli bir şekilde faaliyet gösterildiği, varlık ve kaynakların ...
Osman Çevik, Süleyman Ağmaz
doaj   +1 more source

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