Results 71 to 80 of about 19,291,952 (356)
Screening for lung cancer: A systematic review of overdiagnosis and its implications
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz +12 more
wiley +1 more source
Development of methodological basics of internal control of stocks at the agricultural enterprise [PDF]
Alsou Zakirova +4 more
openalex +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
The article deals with the issues of similarities and differences between the concepts of “internal control” and “internal audit”. The author analyzes the existing approaches in current legislation and current scientific literature, the approaches to ...
Lvova I. G.
doaj
Theoretical grounds of internal audit in the system of state financial control in Ukraine [PDF]
The article considers modern directions of reformation of the system of state financial control connected with introduction of the state internal financial control.
Dikan Larysa V., Kalinkin Dmytro V.
doaj
Internal financial control and internal audit in budget institutions
It is an undeniable fact that the need for continuous improvement in internal auditing and internal financial controls in budgetary institutions is due to the continuous transformation of the Russian Federation's budget model, which requires rational and
I. J. Saifutdinov
doaj
Managing Cyber-Security of in-Bank Ecosystem in Conditions of Digitalization
Information technologies (IT) play a key role in corporate infrastructure. They provide unprecedented economic development of enterprises in our era.
A. D. Bezdelov, E. V. Loginova
doaj +1 more source
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
ERANAN PENGENDALIAN INTERNAL PADA KOPERASI PURLINA KOTA SEMARANG
Tujuan penelitian ini untuk menelaah bagaimana peranan pengendalian internal dalam lingkungan, penilaian risiko, aktivitas pengendalian, informasi dan komunikasi, monitoring/pemantauan di Koperasi Purlina Kota Semarang.
Rizky Widya Astari, Ade Rustiana
doaj

