Results 51 to 60 of about 1,554,751 (318)

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Audit of taxation in the internal control system

open access: yesУченые записки Российской академии предпринимательства, 2021
In this article the author investigates, de jure and de facto, aspects of tax auditing. Due attention is paid to the internal control system of the organization.
A. H. Hamzin, F. S. Rastegaeva
doaj  

Fraud Prevention in Bumdes Fund Management with Internal Locus of Control as a Moderating Variable [PDF]

open access: yesInternational Journal of Management, Accounting and Economics
This study aims to analyze the influence of individual morality and internal control systems on fraud prevention, with internal locus of control as a moderating variable, in Village-Owned Enterprises (BUMDes) in Sumbawa Regency.
Risdan Arianto   +2 more
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Internal Audit and Internal Control Institutions as Legal Prevention Means of Vialations in the Sphere of Economic Financial Activities

open access: yesVestnik Omskoj Ûridičeskoj Akademii, 2012
The article deals with the issues of similarities and differences between the concepts of “internal control” and “internal audit”. The author analyzes the existing approaches in current legislation and current scientific literature, the approaches to ...
Lvova I. G.
doaj  

INTERNAL CONTROL IN SALES ACCOUNTING SYSTEM

open access: yesInovasi, 2022
The importance of internal control in sales recording activities has become a business necessity. Therefore, building an accounting system is a necessity that companies need to build adequate recording facilities, so that company finances are under control.
openaire   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

SYSTEM APPROACH TO INTERNAL QUALITY EDUCATION CONTROL

open access: yesВысшее образование в России, 2016
One of the main conditions of modern education development is continuous improvement of educational quality management. Raising of state and society requirements to specialists“ education, cardinal law reforms and strengthening of state governing and ...
Alexander N. Shkrebko, Inna V. Ivanova
doaj  

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