Results 31 to 40 of about 4,018,197 (309)

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

Maximizing Foundation Effectiveness: Aligning Program Strategy, Organizational Capacity, Strategic Planning, and Performance Assessment to Achieve Success [PDF]

, 2008
This paper outlines a framework for increasing the philanthropic performance of an organization by focusing on strategic planning and development of tight logic models for the organization's programs.
Paul Connolly
core  

SurF: an innovative framework in biosecurity and animal health surveillance evaluation [PDF]

, 2018
Surveillance for biosecurity hazards is being conducted by the New Zealand Competent Authority, the Ministry for Primary Industries (MPI) to support New Zealand's biosecurity system.
Bingham, P, Bullians, M, Gould, B, Muellner, P, Pande, A, Riding, T, Staerk, K D C, Stevens, P, Vink, D, Watts, J   +9 more
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Translating Feedforward Neural Nets to SOM-like Maps [PDF]

, 2003
A major disadvantage of feedforward neural networks is still the difficulty to gain insight into their internal functionality. This is much less the case for, e.g., nets that are trained unsupervised, such as Kohonen¿s self-organizing feature maps (SOMs).
Slump, Kees, Spaanenburg, Lambert, Zwaag, Berend Jan van der   +2 more
core   +2 more sources

Learning strategies scale: adaptation to Portuguese and factor structure [PDF]

, 2018
Since learning strategies seem to be an important set of variables to explain the effectiveness of training and e-learning in organizations is here to stay, this paper aimed to analyze the factor structure and psychometric properties of a Learning ...
Martins, Lara Barros, Medina Díaz, Francisco José, Zerbini, Thaís   +2 more
core   +2 more sources

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego, Kellee Parker, William C. Thomsen, James B. Ford, Mallorie B. Heneghan, David Spencer Mangum, Jennifer L. McNeer, Luke D. Maese, Claire E. F. Miller, Richard Lemons, Taumoha Ghosh   +10 more
wiley   +1 more source

Managing educational sector via self-evaluation policy. Haridussüsteemi juhtimine läbi sisehindamise

Eesti Majanduspoliitilised Väitlused, 2010
Performance evaluation is not a new concept in private sector, while in public sector organisations it has been taken into use since the implementation of performance management.
Kristi Ploom, Reelika Irs
doaj   +1 more source

Applying a matrix of key performance indicators in the evaluation of internal control institutions

Social Development & Security, 2020
The conducted research can be of interest to the specialists of internal audit, internal control, and heads of all levels who organize the functioning of internal control in subordinate structural units.
Анатолій Лойшин
doaj   +1 more source

An Approach Toward the Numerical Evaluation of Multi-Loop Feynman Diagrams [PDF]

, 2001
A scheme for systematically achieving accurate numerical evaluation of multi-loop Feynman diagrams is developed. This shows the feasibility of a project aimed to produce a complete calculation for two-loop predictions in the Standard Model.
't Hooft, 't Hooft, Baikov, Bardin, Bardin, Bashir, Bauberger, Bauberger, Belokurov, Beneke, Berends, Berends, Berends, Berends, Bern, Bern, Bern, Bern, Bern, Bertstein, Binoth, Binoth, Broadhurst, Broadhurst, Broadhurst, Broadhurst, Broadhurst, Broadhurst, Caffo, Caffo, Caffo, Caffo, Caffo, Caffo, Caffo, Caffo, Chetyrkin, Chetyrkin, Chetyrkin, Chetyrkin, Cvitanovic, Davydychev, Davydychev, Degrassi, Degrassi, Degrassi, Devaraj, Eden, Fleischer, Fleischer, Fleischer, Fleischer, Freitas, Freitas, Freitas, Gehrmann, Gehrmann, Gehrmann, Gehrmann, Ghinculov, Ghinculov, Ghinculov, Ghinculov, Giampiero Passarino, Gorishnii, Gorishnii, Groote, Groote, Groote, Groote, Groote, Groote, Heinemeyer, Kazakov, Kotikov, Laporta, Mastrolia, Pais, Passarino, Passarino, Pivovarov, Remiddi, Smirnov, Smirnov, Smirnov, Smirnov, Smirnov, Smirnov, Smirnov, Tarasov, Tarasov, Tarasov, Tarasov, Tarasov, Tkachov, Tkachov, Tkachov, Tkachov, Tkachov, Tkachov, Tkachov, Tkachov, Usyukina, van der Bij, van Ritbergen, Veltman, Vermaseren, Vladimirov   +107 more
core   +2 more sources