Results 41 to 50 of about 4,018,197 (309)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm, Bea Tornberg, Erik Delsing Malmberg, Henrik Hasle, Kristian Løvvik Juul‐Dam, Lars Palmqvist, Borhan R. Saeed, Giti Shah Barkhordar, Anastasia Soboli, Anna Staffas, Jonas Abrahamsson, Linda Fogelstrand   +11 more
wiley   +1 more source

From Internal Evaluation toward Quality Assurance in Distance Higher Education of Iran [PDF]

پژوهش در نظام‌های آموزشی, 2011
Iranian higher education (HE) includes two headquarters named Ministry of Science, Research and Technology and Ministry of Health and Medical education; it also contains about 1500 universities and HE institutions. There are presence and distance courses
Reza Mohammadi, Faranak Mokhtarian, Atefeh Saed   +2 more
doaj  

Persistence of potential ST398 MSSA in outpatient settings among US veterans, 2010–2019

Antimicrobial Stewardship & Healthcare Epidemiology, 2023
Novel ST398 methicillin susceptible Staphylococcus aureus (MSSA) in the United States was first observed in New York City (2004–2007); its diffusion across the country resulted in changing treatment options.
Margaret Carrel, Qianyi Shi, Shinya Hasegawa, Gosia S. Clore, Michael Z. David, Eli N. Perencevich, Matthew Smith, Michihiko Goto   +7 more
doaj   +1 more source

Information systems evaluation in context–impact of the corporate level [PDF]

, 2008
The paper presents the results of a doctoral research related to Information Systems evaluation in context. The authors propose changes in the context, the new level of contextual analysis was added: the system context located between the internal and ...
Irani, Z, Piotrowicz, W
core  

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The Effect of Outcome Selection on the Performance of Prediction Models in Patients at Risk for Sepsis

Critical Care Explorations, 2020
Importance:. Risk prediction models for patients with suspected sepsis have been derived on and applied to various outcomes, including readily available outcomes such as hospital mortality and ICU admission as well as longer-term mortality outcomes that ...
Stephanie P. Taylor, MD, MS, Shih-Hsiung Chou, PhD, Andrew D. McWilliams, MD, MPH, Mark Russo, MD, Alan C. Heffner, MD, Stephanie Murphy, DO, Susan L. Evans, MD, FACS, FCCM, Whitney Rossman, MS, Marc Kowalkowski, PhD, on behalf of Acute Care Outcomes Research Network (ACORN) Investigators, Ryan Brown, Larry Burke, Shih-Hsiung Chou, Kyle Cunningham, Susan L. Evans, Scott Furney, Michael Gibbs, Alan Heffner, Timothy Hetherington, Daniel Howard, Marc Kowalkowski, Scott Lindblom, Andrea McCall, Lewis McCurdy, Andrew McWilliams, Stephanie Murphy, Alfred Papali, Christopher Polk, Whitney Rossman, Michael Runyon, Mark Russo, Melanie Spencer, Brice Taylor, Stephanie Taylor   +33 more
doaj   +1 more source

Patterns of Digoxin Prescribing for Medicare Beneficiaries in the United States 2013-2019

American Journal of Medicine Open, 2023
Background: Studies show that digoxin use is declining but is still prevalent. Recent data on digoxin prescription and characteristics of digoxin prescribers are unknown, which can help understand its contemporary use. Methods: Using Medicare Part D data
Claudia See, Kevin M. Wheelock, César Caraballo, Rohan Khera, Amarnath Annapureddy, Shiwani Mahajan, Yuan Lu, Harlan M. Krumholz, Karthik Murugiah   +8 more
doaj   +1 more source

Evaluation of properties of cast metal foams with irregular inner structure [PDF]

, 2018
Internal structure of metal foams is one of the most important factors that determine its mechanical properties. There exists a number of methods for studying the nature of the inner porous structure.
Hendrych, Jakub, Kroupová, Ivana, Lichý, Petr, Ličev, Lačezar, Souček, Kamil   +4 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source