Results 91 to 100 of about 2,277,571 (305)

YIPFα1A expression is regulated by multilayered molecular mechanisms

open access: yesFEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Dealloying of Platinum-Aluminum Thin Films Part II. Electrode Performance

open access: yes, 2011
Highly porous Pt/Al thin film electrodes on yttria stabilized zirconia electrolytes were prepared by dealloying of co-sputtered Pt/Al films. The oxygen reduction capability of the resulting electrodes was analyzed in a solid oxide fuel cell setup at ...
E. A. Owen   +11 more
core   +1 more source

An argon ion beam milling process for native $\text{AlO}_\text{x}$ layers enabling coherent superconducting contacts [PDF]

open access: yes, 2017
We present an argon ion beam milling process to remove the native oxide layer forming on aluminum thin films due to their exposure to atmosphere in between lithographic steps.
Bilmes, Alexander   +10 more
core   +2 more sources

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Skylab: Cytogenetic studies of blood (experiment mill) [PDF]

open access: yes
Preflight and postflight chromosomal analyses of space flight crews are presented. Special attention is given to findings suggestive of exposure to ionizing radiation.
Lockhart, L. H.
core   +1 more source

Sudden anaerobization in Amphibacillus xylanus increases intracellular labile ferrous iron and inhibits cell growth

open access: yesFEBS Open Bio, EarlyView.
Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata   +13 more
wiley   +1 more source

Association between internal pentachlorophenol exposure characteristics and thyroid hormone indices in a community population in Shanghai, China

open access: yesShanghai yufang yixue
ObjectiveTo assess the level of internal exposure to PCP in a community population in Shanghai, to investigate the factors affecting the level of PCP, and to analyze the correlation between the exposure and thyroid hormone levels.MethodsA total of 464 ...
TAN Yajiao   +8 more
doaj   +1 more source

Post-Glitch RXTE-PCA Observations of the Vela Pulsar

open access: yes, 2000
We report the results of analysis of observations of the Vela Pulsar by PCA on RXTE. Our data consists of two parts. The first part contains observations at 1, 4, and 9 days after the glitch in 1996 and has 27000 sec. total exposure time. The second part
Alpar, M. Ali   +4 more
core   +1 more source

Numerically simulated exposure of children and adults to pulsed gradient fields in MRI [PDF]

open access: yes, 2016
PurposeTo determine exposure to gradient switching fields of adults and children in a magnetic resonance imaging (MRI) scanner by evaluating internal electric fields within realistic models of adult male, adult female, and child inside transverse and ...
Bakker   +22 more
core   +2 more sources

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