Results 61 to 70 of about 549,941 (204)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Digital workflow impact on CAD/CAM crown accuracy: a five-protocol comparison

Brazilian Dental Science
Objective: The objective of this in-vitro study was to assess and compare the marginal adaptation and internal fit of zirconia-reinforced lithium silicate (ZLS) ceramic crowns produced utilising five distinct digital protocols that include multiple ...
Heba Ismail, Seif Elgayar, Ahmad Aboelfadl, Tarek Salah, Nancy Rafla   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Fit of three-unit anterior fixed dental prosthesis frameworks fabricated by different manufacturing techniques

BMC Oral Health
Purpose This in vitro study aimed to evaluate different fabrication techniques for anterior cobalt-chromium (Co-Cr) three-unit fixed dental prostheses (FDPs) and their effects on the fit of maxillary central incisor and canine abutments.
Gürel Pekkan, Hilal Gülgezen Aydın, Süleyman Hakan Tuna, Canan Hekimoğlu   +3 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Comparative analysis of the fit quality of monolithic zirconia veneers produced through traditional and digital workflows using silicone replica technique: an in vitro study

BMC Oral Health
Background The success of a restoration largely depends on the quality of its fit. This study aimed to investigate the fit quality of monolithic zirconia veneers (MZVs) produced through traditional and digital workflows.
Tri Minh Doan, Tan Ngoc Nguyen, Van-Khoa Pham, Natdhanai Chotprasert, Chau Tran Bao Vu   +4 more
doaj   +1 more source

Marginal and internal fit of CAD CAM system: A literature review

Saudi Dental Journal, 2019
The marginal and internal fit are the critical factors for a successful prosthesis. So the aim of this article is to cover all the aspects regarding the measurement methods for the marginal and internal gap, Factors influencing marginal and internal ...
Ahad Al-shalan, Arwa A-lmutair, Diaa Aldin, Shahad Bin-Abbas, Mlaa Al-shmlani, Zahra Asif   +5 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Verification of extraoral versus intraoral scanning techniques: fit accuracy implications for 3D printed and milled zirconia crowns (An in-vitro study)

BMC Oral Health
Background Marginal and internal fit significantly influence the longevity of fixed restorations. This study aims to evaluate the accuracy of extraoral and intraoral scanning techniques for assessing gaps of 3D printed and milled zirconia crowns. Methods
Rogina M. Hassan, Yomna Ibrahim, Rewaa G. AboELHassan, Amir Shoukry Azer   +3 more
doaj   +1 more source

Digital analysis of internal fit variation of additively manufactured crown patterns [PDF]

Exploration of BioMat-X
Aim: The purpose of this study was to digitally quantify the consistency and variation of printed resin crown patterns produced by different 3D printers, aiming to evaluate their clinical relevance and accuracy.
Wendy A. Clark, Mustafa Girnary, Tariq Alsahafi, Ariana Motamedi, Ingeborg J. De Kok   +4 more
doaj   +1 more source