Results 101 to 110 of about 514,802 (301)

Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky, Cara Joyce, H. Jeremy Bockholt, Paul A. Rudnick, William H. Adams, Fiona McAllister, Justin W. Smock, Michael A. Newton, Jane S. Paulsen   +8 more
wiley   +1 more source

Penatalaksanaan Fisioterapi pada Post Open Reduction Internal Fixation Fraktur Femur 1/3 Distal Sinistra di RSUD Panembahan Senopati Bantul [PDF]

, 2018
Fracture is a broken bone or discontinuity of bone tissue,usually experienced because of truama from the outside and mostly due to traffic accidents fracture femur is broken bone on in the femur bone, Open reduction internal fixation (ORIF) is types of ...
, Arin Supriyadi SSTFT, M.FIS, Syauqi, Abdurrafi Fajar   +1 more
core  

The compositional and evolutionary logic of metabolism

, 2012
Metabolism displays striking and robust regularities in the forms of modularity and hierarchy, whose composition may be compactly described. This renders metabolic architecture comprehensible as a system, and suggests the order in which layers of that ...
Alberts B, Andreini C, Balche W E, Barker H A, Benner S A, Berge C, Braakman R, Brazelton W J, Buss L W, Collins M D, Copley S D, Dagley S, Darwin C, de Duve C, Doyle J, Eric Smith, Erwin D H, Feist A M, Fenchel T, Fisher R A, Fry I, Gerhart J, Gesteland R F, Gould S J, Gray H B, Guiral M, Haldane J B S, Kallen R G, Kauffman S, Kim J, Lengeler J W, Ljungdahl L, MacKenzie R E, Martin W, Massey L K, Metzler D E, Morowitz H J, Morowitz H J, Morowitz H J, Nelson D L, Nitscke W, Odling-Smee F J, Oparin A I, Petsko G A, Puigbo P, Ragsdale S, Ragsdale S W, Rankama K, Razin S, Redfield A C, Redfield A C, Rogier Braakman, Russell M J, Schrödinger E, Schuster P, Segré D, Shapiro R, Simon H A, Simon H A, Smith E, Srinivasan V, Srinivasan V, Sterner R W, Stryer L, Szent-Gyorgyi A, Tazuya K, Utter M F, Vogels G D, von Wettstein D, Vorholt J A, Waber L J, Wald G, Wilson E B, Wächtershäuser G, Yarus M, Yi L   +75 more
core   +1 more source

Consistent left gaze bias in processing different facial cues [PDF]

, 2011
While viewing faces, humans often demonstrate a natural gaze bias towards the left visual field, that is, the right side of the viewee’s face is often inspected first and for longer periods.
Guo, Kun, Nicholls, Kelly, Powell, Kathryn, Smith, Claire   +3 more
core   +1 more source

Effectiveness and Safety of Nusinersen and Risdiplam in Spinal Muscular Atrophy: A Systematic Review

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinal Muscular Atrophy (SMA) is a rare genetic disorder marked by progressive muscle weakness and mobility loss. It has a profound physical, emotional and social impact on patients and caregivers, requiring comprehensive medical and supportive care.
Amin Mehrabian, Peter Auguste, Amy Grove, Anna Brown, Janette Parr, Mubarak Patel, Furqan Butt, Jeremiah Donoghue, Mehdi Yousefi, Jo Parsons   +9 more
wiley   +1 more source

Fractures of allografts used in limb preserving operations [PDF]

, 1998
One hundred and thirty-seven allografts used since 1986 in limb preserving operations for malignant bone tumours were reviewed. The follow up was longer than two years.
Cañadell, J.M. (J. M.), San-Julian, M. (Mikel)   +1 more
core  

Longitudinal Relationship Between Pain and Depression in People With Inflammatory Arthritis: A Narrative Review

Arthritis Care &Research, EarlyView.
As many patients with inflammatory arthritis (IA) have chronic pain, understanding how to best assess and manage pain in IA is a priority. Comorbid depression is prevalent in adults with IA, affecting 15% to 39% of people. Although pain and depression are thought to be associated in IA, this concept is largely based on cross‐sectional data.
Natasha Cox, Saeed Farooq, Helen Twohig, Ian C. Scott   +3 more
wiley   +1 more source

Effect of Nonsteroidal Anti‐Inflammatory Drugs on Sacroiliac Joint Inflammation, as Seen on Magnetic Resonance Imaging, in Axial Spondyloarthritis

Arthritis Care &Research, EarlyView.
Objective Imaging evidence of active sacroiliitis is important for diagnosis, classification, and monitoring of axial spondyloarthritis (axSpA). However, there is no consistent guidance on whether patients should temporarily stop nonsteroidal anti‐inflammatory drugs (NSAIDs) before magnetic resonance imaging (MRI).
Gareth T. Jones, Alexander N. Bennett, Raj Sengupta, Pedro M. Machado, Helena Marzo‐Ortega, Lorna Aucott, Margaret A. Hall‐Craggs, Timothy J. P. Bray, Alan Bainbridge, Ruaridh M. Gollifer, Gary J. Macfarlane   +10 more
wiley   +1 more source

Unstable intertrochanteric fracture in elderly patients: outcome of primary cemented bipolar hemiarthroplasty versus internal fixation [PDF]

, 2018
AS Elhadi, YN Gashi
openalex   +1 more source

Posterior Cervical Spine Crisscross Fixation: Biomechanical Evaluation [PDF]

, 2018
Background Biomechanical/anatomic limitations may limit the successful implantation, maintenance, and risk acceptance of posterior cervical plate/rod fixation for one stage decompression-fusion.
Cheng, Joseph S., Cusick, Joseph F., Lifshutz, Jason I., Pintar, Frank A., Yoganandan, Narayan   +4 more
core   +1 more source