Results 81 to 90 of about 263,439 (303)

Biomechanical study of different internal fixation devices for femoral neck fractures: finite element analysis based on different reduction qualities

Frontiers in Bioengineering and Biotechnology
ObjectiveTo compare and analyze the biomechanical advantages and disadvantages of four cannulated screws (4CCS) internal fixation device, biplanar double support screw (BDSF) internal fixation device, and dynamic hip screw (DHS) internal fixation device ...
Zhexi Zhu, Zhexi Zhu, Zhongjian Tang, Zhongjian Tang, Yafei Lu, Yafei Lu, Tao Yang, Tao Yang, Jizhe Lu, Jizhe Lu, Chenglong Pang, Bin Wang   +11 more
doaj   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Internal fixation and comparisons of different fixation methods for treating distal radial fractures in adults [PDF]

, 2013
This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the effectiveness of internal fixation for fractures of the distal radius in skeletally mature people.
Handoll, Helen H.G., Watts, Adam C.; id_orcid, Watts, Adam C., Helen HG Handoll, Adam C Watts   +4 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Internal fixation versus other surgical methods for treating distal radius fractures in adults [PDF]

, 2014
This is the protocol for a review and there is no abstract. The objectives are as follows: To compare the effects (benefits and harms) of internal fixation versus other methods of surgical intervention (percutaneous pinning; external fixation) for distal
Watts, Adam C.; id_orcid, Watts, Adam C., Storey, Philip A., Nuttall, David, Phillips, Alistair R., Jariwala, Arpit C.   +5 more
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

Femoral neck shortening after internal fixation

Acta Orthopaedica et Traumatologica Turcica, 2020
Objective: The aim of this study was to assess the factors affecting femoral neck shortening after internal fixation of femoral neck fractures.\r\nMethods: Eighty-six patients with femoral neck fractures were treated using three parallel cannulated ...
Yue Liu, Zi Sheng AI, Jin Shao, Tieyi Yang   +3 more
doaj   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source