Results 61 to 70 of about 3,647,197 (339)

Orthopaedic surgery [PDF]

, 2005
Over the past fifty years orthopaedic surgery made giant strides forward. It developed from a discipline that dealt primarily with the treatment of fractures, bone infections and tendon transfers and that treated degenerate joints by fusing them to one ...
Grixti, Charles J.
core  

Review article: Risk factors of infection following total knee arthroplasty [PDF]

, 2012
22 PubMed articles in English were identified using the key words: ‘risk factors’, ‘infection’, and ‘primary total knee arthroplasty (TKA)’. The 10 most relevant articles were reviewed. In one study, obesity and diabetes were considered risk factors
Rodríguez Merchán, E. Carlos
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Treatment of Midshaft Clavicle Fractures: Application of Local Autograft With Concurrent Plate Fixation

Arthroscopy Techniques, 2016
Currently, open reduction–internal fixation using contoured plates or intramedullary nails is considered the standard operative treatment for midshaft clavicle fractures because of the immediate rigid stability provided by the fixation device.
Erik L. Slette, B.A., Jacob D. Mikula, B.S., Travis Lee Turnbull, Ph.D., Thomas R. Hackett, M.D.   +3 more
doaj   +1 more source

Reduction of a metapopulation genetic model to an effective one island model [PDF]

, 2018
We explore a model of metapopulation genetics which is based on a more ecologically motivated approach than is frequently used in population genetics. The size of the population is regulated by competition between individuals, rather than by artificially
Alan J. McKane, Crow J. F., César Parra-Rojas, Gardiner C. W., Hanski I., Pielou E. C., van Kampen N. G., Wiggins S., Wright S.   +8 more
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Finite element analysis of retrograde superior ramus screw of pubis for the treament of pelvic anterior ring fracture

Journal of Orthopaedic Surgery and Research
Background Retrograde superior ramus screw of pubis (SRSP) is a new kind of pelvic minimally invasive internal fixation apparatus developed by our team.
Gu Meiqi, Xu Zhe, Li Yifei, Xiang Penghui, Wang Zhen, Zhang Rui, Xin Fei, Tang Zhaohui, Yi Chengla   +8 more
doaj   +1 more source

Clinical efficacy comparison of internal fixation of locking compression plate and cannulated screw in treatment of elderly femoral neck fractures—a retrospective study

Frontiers in Surgery
ObjectiveTo explore the clinical efficacy of internal fixation of locking compression plate and Cannulated Screw in treatment of elderly femoral neck fractures.Methods175 patients with femoral neck fractures admitted to our hospital from January 2022 to ...
Fei Sun, Yu Sun, Wei Li, Zhi Tang, Enxu Liu, Zhaoyong Li, Shaofeng Yang   +6 more
doaj   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Outcomes of total hip arthroplasty, as a salvage procedure, following failed internal fixation of intracapsular fractures of the femoral neck: a systematic review and meta-analysis. [PDF]

, 2016
AIMS: The optimal management of intracapsular fractures of the femoral neck in independently mobile patients remains open to debate. Successful fixation obviates the limitations of arthroplasty for this group of patients.
Archibeck MJ, Blomfeldt R, Broderick JM, Burns PB, Charnley J, Flugsrud GB, Franzén H, Garden RS, Harris WH, Hunt SM, Katz S, McKinley JC, Mehlhoff T, Moher D, Neander G, Nilsson LT, Nilsson LT, Oztürkmen Y, Schmidt AH, Winemaker M, Yang J, Zhang X   +21 more
core   +2 more sources