Results 41 to 50 of about 262,420 (310)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Open reduction internal fixation versus external fixation with limited internal fixation for displaced comminuted closed pilon fractures: A randomised prospective study

Journal of Orthopaedics, Trauma and Rehabilitation, 2018
Background: Pilon fractures involve the dome of the distal tibial articular surface. The optimal treatment for high-energy pilon fractures remains controversial.
Ahmed Rayan, Ahmed Kotb, Elhussein M. Elmoatasem, Shady Samir, Tamer A. EL-Sobky, Ezzat El-Hawi, Mahmoud Mahran   +6 more
doaj   +2 more sources

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Antibiotic artificial bone implantation for the treatment of infection after internal fixation of tibial plateau fractures

BMC Musculoskeletal Disorders, 2022
Objective To explore the clinical effect of antibiotic artificial bone (Calcium phosphate) in the treatment of infection after internal fixation of tibial plateau fractures.
Haotian Hua, Lei Zhang, Zairan Guo, Wenlong Zhong, Jiangfei Chen, Jiangang Guo, Yang Zhang, Peijian Tong, Xinwei Wang   +8 more
doaj   +1 more source

Finite element analysis of the optimal configuration of bridging combined internal fixation system in the treatment of vancouver B1 periprosthetic femoral fractures. [PDF]

, 2021
Long Zhang, Md Ariful Haque, Ying Xiong, Jing Qin, Luyun Liu, Yingjie Zhang, Jiayu Xiao   +6 more
openalex   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Treatment of Midshaft Clavicle Fractures: Application of Local Autograft With Concurrent Plate Fixation

Arthroscopy Techniques, 2016
Currently, open reduction–internal fixation using contoured plates or intramedullary nails is considered the standard operative treatment for midshaft clavicle fractures because of the immediate rigid stability provided by the fixation device.
Erik L. Slette, B.A., Jacob D. Mikula, B.S., Travis Lee Turnbull, Ph.D., Thomas R. Hackett, M.D.   +3 more
doaj   +1 more source

Nonvascular autologous fibular cortical strut graft with internal fixation in monostotic fibrous dysplasia of femur neck- A case report

Journal of Orthopaedic Reports, 2022
Introduction: Fibrous dysplasia is a non-inheritable congenital disorder characterized by bone-forming expansile fibrous lesions that disrupt normal bone architecture.
Mitali Mokashi, Amit Kumar Yadav, Sangeet Gawhale, Farokh Wadia   +3 more
doaj   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Cost Comparison and Complication Rate of Lisfranc Injuries Treated with Open Reduction Internal Fixation versus Primary Arthrodesis

Foot & Ankle Orthopaedics, 2018
Category: Midfoot/Forefoot Introduction/Purpose: Controversy exists regarding optimal primary management of Lisfranc injuries. Whether open reduction internal fixation or primary arthrodesis is superior remains unknown.
Brandon Barnds MD, Bryan Vopat MD, Scott Mullen MD, Paul Schroeppel MD, Brandon Morris MD, Armin Tarakemeh BA   +5 more
doaj   +2 more sources