Results 101 to 110 of about 2,346,149 (306)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Supply chain integration in the product return process: A study of consumer electronics retailers

Acta Commercii, 2017
Background: The increasing complexity and levels of competition facing firms have reiterated the need to integrate the flow of goods and information within and between firms. Limited research has, however, been done regarding this integration in terms of
Wynand Mostert, Wesley Niemann, Theuns Kotzé   +2 more
doaj   +1 more source

Internal centralization and international integration in the post-Soviet space [PDF]

An important but often neglected factor influencing the changes in power relations in Eurasia is the development of center-periphery relations in individual countries.
Libman, Alexander
core   +1 more source

Intercompartmental communication in senescence

FEBS Open Bio, EarlyView.
Senescent cells experience structural changes in the plasma membrane, endoplasmic reticulum, mitochondria, lysosomes, nucleus, and cytoskeleton. These alterations disrupt crosstalk among cellular compartments, impairing vesicular trafficking, contact sites, and molecular flow.
Krystyna Mazan‐Mamczarz, Eleanor J. Wind, Jixiang Leng, Myriam Gorospe   +3 more
wiley   +1 more source

Increased Noise in Cortico-Cortical Integration After Mild TBI Measured With the Equivalent Noise Technique

Frontiers in Neurology, 2019
The bulk of deficits accompanying mild traumatic brain injury (mTBI) is understood in terms of cortical integration—mnemonic, attentional, and cognitive disturbances are believed to involve integrative action across brain regions.
Tatiana Ruiz, Alex S. Baldwin, Daniel P. Spiegel, Robert Hess, Reza Farivar   +4 more
doaj   +1 more source

Multinational Banking in Europe: Financial Stability and Regulatory Implications. Lessons from the Financial Crisis [PDF]

This paper examines whether multinational banks have a stabilising or a destabilising role during times of financial distress. With a focus on Europe, it looks at how these banks‟ foreign affiliates have been faring during the recent financial crisis. It
Alberto Franco Pozzolo, Giacomo Calzolari, Giorgio Barba Navaretti, Micol Levi   +3 more
core  

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

EXPERIENCE OF ROMANIA IN THE ELABORATION AND IMPLEMENTATION OF THE DOMESTIC POLICIES OF EUROPEAN INTEGRATION: LESSONS FOR THE REPUBLIC OF MOLDOVA [PDF]

This article represents an analysis of the experience of Romania in accession and integration of the state into the European Union. It is a tentative to identify Romanian domestic policies of European integration.
Cristina Morari
core