Results 111 to 120 of about 2,346,149 (306)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Project Bundling, Liquidity Spillovers, and Capital Market Discipline [PDF]

This paper develops a theory of integration based on the inability of parties to write comprehensive financial contracts. In our model, integration comes with both benefits and costs.
Holger M. Mueller
core  

Effect of the cosmological constant on the deflection angle by a rotating cosmic string

, 2018
We report the effect of the cosmological constant and the internal energy density of a cosmic string on the deflection angle of light in the spacetime of a rotating cosmic string with internal structure.
Jusufi, Kimet, Övgün, Ali
core   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Impact of EHR direct-to-patient outreach on ambulatory advance directives completion among older adults

BMJ Health & Care Informatics
Background Advance directives (AD) are crucial for aligning healthcare with end-of-life preferences, yet documentation rates remain low, often only 5–15%.
Karen Brown, Nancy Kim, Andrew Pugliese, Abby Dancause, Rita Amendola   +4 more
doaj   +1 more source

Facilitators and Barriers to the Integration of Healthcare Service and Building Design [PDF]

Service design research recognises the importance of infrastructure design in the achievement of streamlined service delivery. Although research about service design and building design is abundant, very little is known about the integration of these ...
Codinhoto, Ricardo, Kagioglou, Mike, Koskela, Lauri, Rooke, John, Tzortzopoulos, Patricia   +4 more
core  

Global integration of the Schr\"odinger equation: a short iterative scheme within the wave operator formalism using discrete Fourier transforms

, 2015
A global solution of the Schr\"odinger equation for explicitly time-dependent Hamiltonians is derived by integrating the non-linear differential equation associated with the time-dependent wave operator.
Jolicard, Georges, Leclerc, Arnaud
core   +3 more sources

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

PENGARUH INTEGRASI INTERNAL, INTEGRASI EKSTERNAL, DAN EFEK KOMPLEMENTER INTEGRASI DALAM RANTAI PASOKAN TERHADAP INOVASI PRODUK

MIX: Jurnal Ilmiah Manajemen, 2017
. This research examines the individual and combined effects of internal integration (II) and external integration (IE) on product innovation (IP), which is based on ambidexterity theory.
Zulaeha Zulaeha, Anjar Priyono
doaj  

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

Aging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel, S. Tissera, E. Paul, J. Zalcberg, R. G. Stirling   +4 more
wiley   +1 more source