Results 51 to 60 of about 398,308 (298)

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

Comparison of Three Different Techniques of Inverted Internal Limiting Membrane Flap in Treatment of Large Idiopathic Full-Thickness Macular Hole. [PDF]

, 2019
Purpose: To evaluate and compare three different techniques of inverted internal limiting membrane (ILM) flap in the treatment of large idiopathic full-thickness macular hole. Methods: In a comparative interventional case series, 72 eyes from 72 patients
Dalvin, Lauren A., Ghassemi, Fariba, Khodabande, Alireza, Khojasteh, Hassan, Mazloumi, Mehdi, Mirghorbani, Masoud, Riazi-Esfahani, Hamid   +6 more
core   +1 more source

Theory of voltammetry in charged porous media

, 2018
We couple the Leaky Membrane Model, which describes the diffusion and electromigration of ions in a homogenized porous medium of fixed background charge, with Butler-Volmer reaction kinetics for flat electrodes separated by such a medium in a simple ...
Bazant, Martin Z., Khoo, Edwin
core   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Technology of Inverted Internal Limi ting Membrane Flap in Surgery of Primary Through Macular Retinal Holes. Literature Review

Oftalʹmologiâ
A review of the literature describes various approaches to peeling the internal limiting membrane of the retina in the surgical treatment of penetrating macular holes.
N. M. Shilov, A. V. Tereschenko, N. N. Yudina, S. V. Novikov, S. Z. Kabuldinova   +4 more
doaj   +1 more source

Does internal limiting membrane peeling during epiretinal membrane surgery induce microscotomas on microperimetry? Study protocol for PEELING, a randomized controlled clinical trial

Trials, 2020
Background The epiretinal membrane (ERM) is a degenerative condition associated with age, which can cause loss of vision and/or metamorphopsia. The treatment of symptomatic ERM involves surgical removal including a vitrectomy followed by peeling of the ...
Jean-Baptiste Ducloyer, Juliette Ivan, Alexandra Poinas, Olivier Lebreton, Alexandre Bonissent, Paul Fossum, Christelle Volteau, Ramin Tadayoni, Catherine Creuzot-Garchet, Yannick Le Mer, Julien Perol, June Fortin, Anne Chiffoleau, Fanny Billaud, Catherine Ivan, Michel Weber   +15 more
doaj   +1 more source

Overlimiting Current and Shock Electrodialysis in Porous Media

, 2013
Most electrochemical processes, such as electrodialysis, are limited by diffusion, but in porous media, surface conduction and electro-osmotic flow also contribute to ionic fluxes.
Bazant, Martin Z., Deng, Daosheng, Dydek, E. Victoria, Han, Ji-Hyung, Mani, Ali, Schlumpberger, Sven, Zaltzman, Boris   +6 more
core   +1 more source

A Review of Innovations in Rhegmatogenous Retinal Detachment Surgical Techniques. [PDF]

, 2017
Rhegmatogenous retinal detachment (RRD) requires surgical intervention for its repair. There are variable techniques used for this purpose, and they are all being continuously refined.
Loewenstein, Anat, Moisseiev, Elad, Moshiri, Ala, Nemet, Achia, Yiu, Glenn   +4 more
core   +3 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Attractor Metadynamics in Adapting Neural Networks

, 2014
Slow adaption processes, like synaptic and intrinsic plasticity, abound in the brain and shape the landscape for the neural dynamics occurring on substantially faster timescales.
C. Gros, C. Gros, C. Gros, C.J. Honey, D. Marković, E. Marder, E. Russo, E.T. Jaynes, G. Daoudal, G. Deco, G.G. Turrigiano, J. Triesch, J.J. Hopfield, J.J. Steil, M. Linkerhand, N. Ulanovsky, R.D. Beer, R.D. Beer, R.D. Beer, T. O’Leary   +19 more
core   +1 more source