Results 91 to 100 of about 1,428,004 (304)

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Skin Temperature as a Marker of Physical Fitness Profile: The Impact of High-Speed Running in Professional Soccer Players

Sports
High-speed running (HSR) has the greatest physiological impact on soccer players. It is closely linked to neuromuscular fatigue and muscle damage post-match, emphasizing the role that load monitoring plays in both performance and recovery.
Victor-Luis Escamilla-Galindo, Armiche Vega-Ramos, Jose Luis Felipe, Antonio Alonso-Callejo, Ismael Fernandez-Cuevas   +4 more
doaj   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

The The influence of age and refereeing experience on the official matches’ physical and physiological responses of football referees

European Journal of Human Movement
This study analyzed the influence of age, refereeing experience, and experience at the current competitive level on amateur football referees’ physical and physiological responses.
Eñaut Ozaeta-Beaskoetxea, Daniel Castillo, Aitor Pinedo-Jauregi, Jon Mikel Picabea, Javier Yanci   +4 more
doaj   +1 more source

Gamma-Ray Burst without Baryonic and Magnetic Load?

, 2011
We show that, contrary to common belief, internal shocks can arise in an accelerating radiation-dominated jet if it is confined even weakly to a converging opening angle because the acceleration declines.
Ioka, Kunihito, Kawanaka, Norita, Mizuta, Akira, Ohira, Yutaka   +3 more
core   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Dance-Specific Patterns of Relative Oxygen Uptake in Elite Slovak Standard and Latin DanceSport Dancers

Applied Sciences
Background: DanceSport involves intermittent high-intensity efforts that may differ between styles and partners within a dance couple. However, dance-specific relative oxygen uptake (%VO2max) in elite Standard and Latin dancers remains insufficiently ...
Matej Chren, Milan Špánik, Viktor Plačko, Adéla Chlapcová, Peter Olej, Szymon Kuliś   +5 more
doaj   +1 more source

The strain energy analysis of swept boxes with ribs normal to the spars [PDF]

, 1953
The root constraint problem associated with uniform rectangular swept boxes, having ribs normal to the spars is considered. A strain energy method using self-equilibrating internal end load systems is used. Continues
Howe, D.
core  

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source