Results 91 to 100 of about 328,233 (261)
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
FEBS Open Bio, EarlyView.BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
New Directions for Adult and Continuing Education, EarlyView.ABSTRACT This article examines the evolving role of organizational leadership amidst the rapid advancements in artificial intelligence (AI). It explores a broadly experienced and documented crisis in leadership, due in part to the disruptive nature of AI and emerging technology.
Rachel Wlodarsky, Davin Carr Chellman
wiley +1 more source
Location‐Specific Hematoma Volume Predicts Early Neurological Deterioration in Supratentorial ICH
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Early neurological deterioration (END) adversely affects outcomes in patients with intracerebral hemorrhage (ICH). This study aimed to determine the location‐specific hematoma volumes for END in supratentorial ICH patients. Methods We retrospectively analyzed supratentorial ICH patients presenting from two prospective cohorts.
Zuoqiao Li +10 more
wiley +1 more source
Analysis of the External and Internal Load in Professional Basketball Players. [PDF]
Sports (Basel), 2023 Gamonales JM +3 more
europepmc +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang +8 more
wiley +1 more source
Variability in the Load of Professional Basketball Referees during Competition
Applied SciencesMonitoring the demands on basketball referees is essential for optimizing their performance and reducing the risk of injuries. This study aimed to analyze the workload experienced by elite basketball referees during official games.
Sergio José Ibáñez +3 more
doaj +1 more source
Love numbers for internal loading
Love numbers used in the paper "GRACE detection of rapid mass redistributions during a mineral phase transition in the deep mantle" by Gaugne et al., 2025.
openaire +1 more source
Distributed loads alter internal load predictions in the hands and forearm
Computer Methods in Biomechanics and Biomedical EngineeringThis study examined the influence of distributed external hand forces joint moments and muscle activation. Kinematics and forces were collected during multiple finger tasks while surface pressure was measured to create 3 force input models in OpenSim: (1) segment centre of mass (CM), (2) centre of pressure (CP), and (3) single point force on each digit
Chhiba, Ryan +2 more
openaire +1 more source
CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao +7 more
wiley +1 more source
SensorsTechnological development has boosted the use of multi-sensor devices to monitor athletes’ performance, but the location and connectivity between devices have been shown to affect data reliability.
Joaquín Martín Marzano-Felisatti +4 more
doaj +1 more source