Results 71 to 80 of about 328,233 (261)

Dance-Specific Patterns of Relative Oxygen Uptake in Elite Slovak Standard and Latin DanceSport Dancers

Applied Sciences
Background: DanceSport involves intermittent high-intensity efforts that may differ between styles and partners within a dance couple. However, dance-specific relative oxygen uptake (%VO2max) in elite Standard and Latin dancers remains insufficiently ...
Matej Chren, Milan Špánik, Viktor Plačko, Adéla Chlapcová, Peter Olej, Szymon Kuliś   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Sensor-Based Monitoring of Heart-Rate Responses to Ball Type in 9–11-Year-Old Tennis Players: A Preliminary Bayesian Repeated-Measures Study

Sensors
Understanding internal load in youth tennis is essential for optimizing training strategies and ensuring healthy development. This study analyzed the influence of ball type (green vs.
Ana Piquer-Piquer, José María Giménez-Egido, José Francisco Guzmán, Miguel Crespo, Manrique Rodríguez-Campos, Rafael Martínez-Gallego   +5 more
doaj   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline

FEBS Open Bio, EarlyView.
Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey, Vaishnavi Sanjayan, Praveen Singh, Shantanu Sengupta, Anand Kumar Bachhawat   +4 more
wiley   +1 more source

Modelling Energy Demands of Cross-Country Tests in 2-Star to 5-Star Eventing Competitions

Animals
Eventing is an Olympic equestrian discipline comprising dressage, cross-country, and show jumping, with the cross-country phase imposing the greatest physical demands on horses.
Anna M. Liedtke, Hans Meijer, Stephanie Horstmann, Caroline von Reitzenstein, Insa Rump, Katharina Kirsch   +5 more
doaj   +1 more source

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Heart Rate Measurement Accuracy During Intermittent Efforts Under Laboratory Conditions: A Comparative Analysis Between Chest Straps and Armband

Applied Sciences
Heart rate (HR) is the most frequently used variable to monitor athletes’ internal load during training and competition. High-intensity effort and abrupt HR changes during exercise have presented measurement accuracy issues depending on the chosen device.
Joaquín Martín Marzano-Felisatti, Leonardo De Lucca, José Ignacio Priego-Quesada, José Pino-Ortega   +3 more
doaj   +1 more source