Results 71 to 80 of about 361,972 (301)

Distortion Load Identification Based on the Application of Compensating Devices

Energies, 2020
The article provides an analysis of the existing methods of identifying the consumer’s contribution to voltage distortion at a point of common coupling.
Yaroslav Shklyarskiy, Aleksandr Skamyin, Iaroslav Vladimirov, Farit Gazizov   +3 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Predicting the consequences of our own actions: the role of sensorimotor context estimation [PDF]

, 1998
During self-generated movement it is postulated that an efference copy of the descending motor command, in conjunction with an internal model of both the motor system and environment, enables us to predict the consequences of our own actions (von ...
Goodbody, SJ, Wolpert, DM, Wolpert, D.M., Blakemore, SJ, Blakemore, S.J., Goodbody, S.J.   +5 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

Molecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens, Anouk Mentink, Tom Niessink, Frank Coumans, Leonie Mekenkamp, Ruchi Bansal, Jeroen Hiltermann   +6 more
wiley   +1 more source

Validity of Session Rating Perceived Exertion Method for Quantifying Internal Training Load during High-Intensity Functional Training

, 2018
The aim of this study was to validate the quantification of internal training load (session rating perceived exertion, sRPE) and the effect of recall timing of sRPE during high-intensity functional training (HIFT) sessions.
Gabbett, Timothy J., Ramires Tibana, Prestes, Jonato, Voltarelli, Fabricio, Tim Gabbett, Jonato Prestes, Gabriel Cunha, de Sousa, Nuno, Gabbett, Tim, Tim J. Gabbett, Ramires Alsamir Tibana, Nuno De Sousa, Tibana, Ramires Alsamir, Cunha, Gabriel Veloso, Nuno Manuel Frade de Sousa, Fabrício Voltarelli, Frade de Sousa, Nuno Manuel, Fabrício Azevedo Voltarelli, Voltarelli, Fabricio Azevedo, Gabriel Veloso Cunha, Tibana, Ramires, Fett, Carlos, Carlos Fett, Cunha, Gabriel   +23 more
core   +1 more source

Internal and external scripts in computer-supported collaborative inquiry learning [PDF]

, 2007
We investigated how differently structured external scripts interact with learners’ internal scripts concerning individual knowledge acquisition in a Web-based collaborative inquiry learning environment.
Slotta, J. D., Kollar, Ingo, Fischer, Frank, Slotta, James D., Slotta, James D   +4 more
core   +1 more source

Correlation between Perceived Exertion, Wellness Scores, and Training Load in Professional Football across Microcycle Durations

Applied Sciences
Perceived exertion (RPE, RPEdur) and wellness scores (Hooper) are common methods to assess the training load and readiness in football. However, in professional football, there is a lack of data concerning the application of these tools in microcycles of
Lazaros Vardakis, Marianthi Koutsokosta, Yiannis Michailidis, Charalambos Zelenitsas, Panagiotis Topalidis, Thomas I. Metaxas   +5 more
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Unifying prospective and retrospective interval-time estimation: a fading-gaussian activation-based model of interval-timing [PDF]

, 2014
Hass and Hermann (2012) have shown that only variance-based processes will lead to the scalar growth of error that is characteristic of human time judgments.
Mareschal, Denis, Addyman, Caspar, Thomas, Elizabeth, French, R.M., Thomas, E., French, Robert M.   +5 more
core   +1 more source