Results 51 to 60 of about 3,882,696 (292)

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

A Comparison of Mean and Peak Internal Training and Competition Physical Demands in Professional Male Basketball Players

Applied Sciences
Purpose: The main aim of this study was to compare the average and peak values of heart rate [HR], oxygen consumption [VO2], and respiratory rate [RR] of professional basketball players between practices and competition.
Enrique Alonso-Pérez-Chao, Rubén Portes, Sergio L. Jiménez-Sáiz, Carlos Ribas, Neus Llinás, Adrián López-García, Alberto Lorenzo   +6 more
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Does fatigue mask directional performance asymmetry? Preferred and non-preferred throwing-side differences during judo-specific tasks in young judo athletes

Revista de Artes Marciales Asiáticas
The aim of this study was to examine whether fatigue influences performance differences between the preferred and non-preferred throwing sides during judo-specific tasks in young judo athletes.
Salih Karaman, Şükrü Serdar Balci
doaj   +1 more source

Analysis of external load and internal load in AirBadminton

Sustainability and Sports Science Journal
The aim of this study was to compare internal load and external load between AirBadminton and traditional indoor badminton. The research was conducted with 8 badminton players from the Alicante Technification Centre, including both men and women. The study was carried out based on the recommendations and guidelines of the International Badminton ...
Carlos Elvira Aranda, José Antonio Pérez-Turpin, María José Gomis Gomis, Mario Amatria Jiménez   +3 more
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Can load carriage system weight, design and placement affect pain and discomfort? A systematic review [PDF]

, 2011
Purpose: A systematic review of the literature was conducted to answer the following questions: 1. Does usage or weight of load carriage system cause pain, perceived exertion or discomfort? 2.
Golriz, S., Walker, B.
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