Results 61 to 70 of about 1,428,004 (304)

Internal viscoelastic loading in cat papillary muscle

open access: yesBiophysical Journal, 1982
The passive mechanical properties of myocardium were defined by measuring force responses to rapid length ramps applied to unstimulated cat papillary muscles. The immediate force changes following these ramps recovered partially to their initial value, suggesting a series combination of viscous element and spring.
Chiu, Y.L., Ballou, E.W., Ford, L.E.
openaire   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The International Mass Loading Service [PDF]

open access: yes, 2015
The International Mass Loading Service computes four loadings: a) atmospheric pressure loading; b) land water storage loading; c) oceanic tidal loading; and d) non-tidal oceanic loading. The service provides to users the mass loading time series in three forms: 1) pre-computed time series for a list of 849 space geodesy stations; 2) pre-computed time ...
openaire   +2 more sources

Monitoring Internal and External Load During Volleyball Competition

open access: yesInternational Journal of Sports Physiology and Performance, 2022
Purpose: The aim of this study was to identify the relationships between continuously measured internal and external load variables during volleyball competition. Methods: A total of 8 male elite volleyball athletes (Belgian Liga A and Liga B) were monitored during official competition matches.
Gielen, Jasper   +4 more
openaire   +3 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

A comparison of variable valve strategies at part load for throttled and un-throttled SI engine configurations [PDF]

open access: yes, 2015
The presented work concerns the study of the fuel consumption and emissions benefits achieved at part load by employing a fully variable valve train in a 1.6L SI gasoline engine.
Barber, M, Cairns, A, Pesiridis, A
core   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Distortion Load Identification Based on the Application of Compensating Devices

open access: yesEnergies, 2020
The article provides an analysis of the existing methods of identifying the consumer’s contribution to voltage distortion at a point of common coupling.
Yaroslav Shklyarskiy   +3 more
doaj   +1 more source

Methods of resistance estimation in permanent magnet synchronous motors for real-time thermal management [PDF]

open access: yes, 2010
Real-time thermal management of electrical ma- chines relies on sufficiently accurate indicators of internal tem- perature. One indicator of temperature in a permanent-magnet synchronous motor (PMSM) is the stator winding resistance.
Stewart, Paul   +2 more
core   +3 more sources

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