Results 91 to 100 of about 4,759,037 (353)

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Blocked Atrial Bigeminy as an Unusual Cause of Bradycardia: A Case Report

International Medical Case Reports Journal
Oleksii Skakun,1 Ihor Vandzhura,2 Yaroslava Vandzhura,2 Roksolana Denina,2 Pavlo Zvonar2 1Cardiological Department, St. Luke’s Clinic, Ivano-Frankivsk, Ukraine; 2Department of Internal Medicine No.
Skakun O, Vandzhura I, Vandzhura Y, Denina R, Zvonar P   +4 more
doaj  

Antibiotic Knowledge, Perception, and Practice of Intern Doctors in Turkey:  A Survey Study

ASIDE Internal Medicine
Background: This study aimed to measure intern doctors' knowledge, attitudes, and perceptions about antibiotic treatment and determine the situation on the subject.
AHMET DOĞAN, Azra SÖNMEZ, Beyza DİŞLİ, Hasan Şamil ÇELİK, Chingiz RUSTAMLİ, Ecem Berra NAZLIOĞLU, Zuhat ABDULKERİMOĞLU, Mustafa Talha ALTUNBAŞ, Rumeysa ÖZER   +8 more
doaj   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Surviving Unrepaired Tetralogy of Fallot to 43 Years in a Low-Resource Setting: The Oldest Reported Case from Somalia

International Medical Case Reports Journal
Abdirahman A Warfaa,1 Abdirahman Ibrahim Said,1 Mohamoud Abdulahi,1 Mohamed Said Hassan1,2 1College of Health Science, School of Medicine, Amoud University, Borama, Somalia; 2School of Postgraduate Studies and Research, Amoud University, Borama ...
Warfaa AA, Said AI, Abdulahi M, Hassan MS   +3 more
doaj  

The Impact of Idiopathic Intracranial Hypertension on Cardiovascular Disease Risk Among UK Women: An Obesity-Adjusted Analysis

ASIDE Internal Medicine
Introduction: Idiopathic intracranial hypertension (IIH) is known to elevate cardiovascular disease (CVD) risk, but the extent to which obesity and IIH-specific factors contribute to this risk is not well understood.
Ahmed Y. Azzam, Mahmoud M. Morsy, Mohamed Hatem Ellabban, Ahmed M. Morsy, Adham Adel Zahran, Mahmoud Nassar, Omar S. Elsayed, Adam Elswedy, Osman Elamin, Ahmed Saad Al Zomia, Hana J. Abukhadijah Abukhadijah, Hammam A. Alotaibi Alotaibi, Oday Atallah, Mohammed A. Azab, Muhammed Amir Essibayi, Adam A. Dmytirw, Mohamed D. Morsy, David J. Altschul   +17 more
doaj   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Isolated Diffuse Splenic Hemangiomatosis Arising in an Adolescent: A Rare Case Report and Literature Review

Pediatric Health, Medicine and Therapeutics
Zhuping Chen,1 Dongdong Zhang1,2 1Department of Hematology, Postgraduate Union Training Base of Xiangyang No.1 People’s Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, Hubei, 441000, People’s Republic of China ...
Chen Z, Zhang D
doaj  

Lifestyle Practices in Reducing Cardiovascular Diseases: A Prospective Cohort Study from Pakistan

ASIDE Internal Medicine
Background: Cardiovascular diseases (CVD) remain the leading cause of global mortality, especially in individuals with comorbidities like type II diabetes and hypertension.
Humna Shahid, Muhammad Saqib, Muhammad Iftikhar, Shehr I Yar Khan, Muhammad Ahsan, Hashir Ali Shah, Umama Amjad, Muhammad Nadeem Khan, Saiyad Ali, Hassan Mumtaz   +9 more
doaj   +1 more source

Evolutionary dynamics of the chloroplast genome in Daphne (Thymelaeaceae): comparative analysis with related genera and insights into phylogenetics

FEBS Open Bio, EarlyView.
Comparative analysis of chloroplast genomes from 14 genera of Thymelaeaceae revealed variation in gene content, ranging from 128 to 142 genes, primarily influenced by IR expansion/contraction events and pseudogenization of ndhF, ndhI, and ndhG. Two large inversions were detected within the large single‐copy region, including a synapomorphic inversion ...
Abdullah, Hui Li, Rushan Yan, Chengyu Chen, Madiha Islam, Abdul Majid, Ibrar Ahmed, Parviz Heidari, Xiaoxuan Tian   +8 more
wiley   +1 more source