Results 71 to 80 of about 3,366,641 (267)

Short-Term Changes in Hematologic Inflammatory Indices During Exenatide Therapy in Patients with Type 2 Diabetes Mellitus

ASIDE Internal Medicine
Background: Inflammation plays an important role in the pathogenesis of type 2 diabetes mellitus (T2DM) and the development of complications. Glucagon-like peptide-1 receptor agonists (GLP-1RAs) are widely used to treat T2DM. Mean platelet volume (MPV),
Cigdem Cindoglu, Hüseyin Karaaslan, Nida Uyar, Ali Gökçe, Burcu Dikeç Gökçe, Mehmet Ali Eren   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Surviving Unrepaired Tetralogy of Fallot to 43 Years in a Low-Resource Setting: The Oldest Reported Case from Somalia

International Medical Case Reports Journal
Abdirahman A Warfaa,1 Abdirahman Ibrahim Said,1 Mohamoud Abdulahi,1 Mohamed Said Hassan1,2 1College of Health Science, School of Medicine, Amoud University, Borama, Somalia; 2School of Postgraduate Studies and Research, Amoud University, Borama ...
Warfaa AA, Said AI, Abdulahi M, Hassan MS   +3 more
doaj  

Efficacy and Safety of Penehyclidine Hydrochloride in Postoperative Nausea and Vomiting Prevention: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

ASIDE Internal Medicine
Introduction: Postoperative nausea and vomiting (PONV) is a common complication following anesthesia. Penehyclidine hydrochloride (PHC), an anticholinergic medication, selectively inhibits the M1 Muscarinic and M3 Muscarinic receptors involved in the ...
Ahmed Magdy, Eithar Alqady, Mohamed Wagdy, Ahmed T.shalby, Mahmoud Abdelkader, Karim Osamy, Alaa Anter, IhabTarik, Manar Samy, Sherif Eltawansy, Ahmed Hassan   +10 more
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Isolated Diffuse Splenic Hemangiomatosis Arising in an Adolescent: A Rare Case Report and Literature Review

Pediatric Health, Medicine and Therapeutics
Zhuping Chen,1 Dongdong Zhang1,2 1Department of Hematology, Postgraduate Union Training Base of Xiangyang No.1 People’s Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, Hubei, 441000, People’s Republic of China ...
Chen Z, Zhang D
doaj  

Antibiotic Knowledge, Perception, and Practice of Intern Doctors in Turkey:  A Survey Study

ASIDE Internal Medicine
Background: This study aimed to measure intern doctors' knowledge, attitudes, and perceptions about antibiotic treatment and determine the situation on the subject.
AHMET DOĞAN, Azra SÖNMEZ, Beyza DİŞLİ, Hasan Şamil ÇELİK, Chingiz RUSTAMLİ, Ecem Berra NAZLIOĞLU, Zuhat ABDULKERİMOĞLU, Mustafa Talha ALTUNBAŞ, Rumeysa ÖZER   +8 more
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

The Impact of Idiopathic Intracranial Hypertension on Cardiovascular Disease Risk Among UK Women: An Obesity-Adjusted Analysis

ASIDE Internal Medicine
Introduction: Idiopathic intracranial hypertension (IIH) is known to elevate cardiovascular disease (CVD) risk, but the extent to which obesity and IIH-specific factors contribute to this risk is not well understood.
Ahmed Y. Azzam, Mahmoud M. Morsy, Mohamed Hatem Ellabban, Ahmed M. Morsy, Adham Adel Zahran, Mahmoud Nassar, Omar S. Elsayed, Adam Elswedy, Osman Elamin, Ahmed Saad Al Zomia, Hana J. Abukhadijah Abukhadijah, Hammam A. Alotaibi Alotaibi, Oday Atallah, Mohammed A. Azab, Muhammed Amir Essibayi, Adam A. Dmytirw, Mohamed D. Morsy, David J. Altschul   +17 more
doaj   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source