Results 71 to 80 of about 4,796,409 (286)

Real-World Epidemiological Analysis of Gastrointestinal Neuroendocrine Carcinomas: A TriNetX-Based Study

ASIDE Internal Medicine
Introduction: Gastrointestinal neuroendocrine carcinomas (GI-NECs) are a diverse group of aggressive tumors with variable clinical outcomes. Although progress has been made in classifying and treating these cancers, detailed real-world data on their
Bahaaeldin Baraka, Mahmoud Nassar, Ahmed Y. Azzam, Mahmoud M. Morsy, Eyad Ibrahim, Jin Wu, Ahmad Ghorab   +6 more
doaj   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Isolated Diffuse Splenic Hemangiomatosis Arising in an Adolescent: A Rare Case Report and Literature Review

Pediatric Health, Medicine and Therapeutics
Zhuping Chen,1 Dongdong Zhang1,2 1Department of Hematology, Postgraduate Union Training Base of Xiangyang No.1 People’s Hospital, School of Medicine, Wuhan University of Science and Technology, Xiangyang, Hubei, 441000, People’s Republic of China ...
Chen Z, Zhang D
doaj  

Dexmedetomidine as an Adjuvant to Ropivacaine in Thoracic Paravertebral Block: A Systematic Review with Meta-analysis

ASIDE Internal Medicine
Background: One of the ongoing challenges in thoracic surgeries, especially video-assisted thoracoscopic surgery (VATS), is effective postoperative pain management.
Mohamed Wagdy, Abdelrahman Abdalla Mohamed, Abdalla Ahmed Mohamed, Ziad ElDosoky Farouk, Mahmoud Abd El Nasser, Abdelrahman A. Ebaid Ebaid, Abdelrhman Waleed Kotb , Mostafa AbdElmawla Mohamed   +7 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Dual Use of Electronic Cigarettes and Cigarettes Elevates Risk of Chronic Obstructive Pulmonary Disease and Mental Health Issues: Insights from a Korean Health Survey

International Journal of COPD
Chi Young Kim,1 Sang Ho Park,2 Yeseul Seong,3 Yong Jun Choi,1 Hye Jung Park,1 Jae Hwa Cho,1 Min Kwang Byun1 1Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Department of Clinical Research Design and ...
Kim CY, Park SH, Seong Y, Choi YJ, Park HJ, Cho JH, Byun MK   +6 more
doaj  

Investigating Racial Disparities in Insulin Pump Use Among People with Type 1 Diabetes Across the United States: A Retrospective Multicenter Study

ASIDE Internal Medicine
Introduction: Despite technological advances in Type 1 Diabetes Mellitus (T1D) management, racial disparities in insulin pump utilization persist. We investigated patterns of insulin pump adoption across different racial groups using a large-scale ...
Mahmoud Nassar, Ahmed Y. Azzam, Mahmoud M. Morsy, Iqra Patoli, Angad Gill, Erlin Marte   +5 more
doaj   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Respiratory Syncytial Virus Vaccine Induced Thrombotic Microangiopathy

Journal of Blood Medicine
Robert Seby,1 Benjamin J McCormick,1 Emily Wolf,2 Justin Kuhlman,2 Nikita Jhawar,1 Sven Peter Oman,1 Adam M Kase,2 Chancey Christenson,3 Marwan Shaikh2 1Department of Internal Medicine, Mayo Clinic, Jacksonville, FL, USA; 2Department of Hematology ...
Seby R, McCormick BJ, Wolf E, Kuhlman J, Jhawar N, Oman SP, Kase AM, Christenson C, Shaikh M   +8 more
doaj  

Prevalence of Metabolic-Associated Steatotic Liver Disease in Patients with Type 2 Diabetes with and without HIV: Retrospective Multicenter Study

ASIDE Internal Medicine
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a frequent complication in patients with Type 2 Diabetes (T2D). This study aims to evaluate the impact of HIV status on the prevalence of MASLD in patients with T2D ...
Hazem Abosheaishaa, Omar Nassar, Mostafa Alfishawy, Anthony Martinez   +3 more
doaj   +1 more source