Results 61 to 70 of about 3,366,641 (267)

Real-World Epidemiological Analysis of Gastrointestinal Neuroendocrine Carcinomas: A TriNetX-Based Study

ASIDE Internal Medicine
Introduction: Gastrointestinal neuroendocrine carcinomas (GI-NECs) are a diverse group of aggressive tumors with variable clinical outcomes. Although progress has been made in classifying and treating these cancers, detailed real-world data on their
Bahaaeldin Baraka, Mahmoud Nassar, Ahmed Y. Azzam, Mahmoud M. Morsy, Eyad Ibrahim, Jin Wu, Ahmad Ghorab   +6 more
doaj   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Dexmedetomidine as an Adjuvant to Ropivacaine in Thoracic Paravertebral Block: A Systematic Review with Meta-analysis

ASIDE Internal Medicine
Background: One of the ongoing challenges in thoracic surgeries, especially video-assisted thoracoscopic surgery (VATS), is effective postoperative pain management.
Mohamed Wagdy, Abdelrahman Abdalla Mohamed, Abdalla Ahmed Mohamed, Ziad ElDosoky Farouk, Mahmoud Abd El Nasser, Abdelrahman A. Ebaid Ebaid, Abdelrhman Waleed Kotb , Mostafa AbdElmawla Mohamed   +7 more
doaj   +1 more source

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

Molecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang, Hyung Seok Kim, Geum Ok Baek, Moon Gyeong Yoon, Su In Lee, Jee‐Yeong Jeong, Ji Eun Han, Soon Sun Kim, Jae Youn Cheong, Jung Woo Eun   +9 more
wiley   +1 more source

Investigating Racial Disparities in Insulin Pump Use Among People with Type 1 Diabetes Across the United States: A Retrospective Multicenter Study

ASIDE Internal Medicine
Introduction: Despite technological advances in Type 1 Diabetes Mellitus (T1D) management, racial disparities in insulin pump utilization persist. We investigated patterns of insulin pump adoption across different racial groups using a large-scale ...
Mahmoud Nassar, Ahmed Y. Azzam, Mahmoud M. Morsy, Iqra Patoli, Angad Gill, Erlin Marte   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Clinical Characteristics and Risk Factors for Progressive Pulmonary Fibrosis in Primary Sjögren’s Syndrome: A Case-Control Study

Risk Management and Healthcare Policy
Jianping Diao,1,2 Lin Qiao,1 Xinwang Duan,3 Min Hui,4 Mengtao Li,1 Yan Zhao,1 Xiaofeng Zeng,1 Dong Xu1 1Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union ...
Diao J, Qiao L, Duan X, Hui M, Li M, Zhao Y, Zeng X, Xu D   +7 more
doaj  

Prevalence of Metabolic-Associated Steatotic Liver Disease in Patients with Type 2 Diabetes with and without HIV: Retrospective Multicenter Study

ASIDE Internal Medicine
Introduction: Metabolic dysfunction-associated steatotic liver disease (MASLD) is a frequent complication in patients with Type 2 Diabetes (T2D). This study aims to evaluate the impact of HIV status on the prevalence of MASLD in patients with T2D ...
Hazem Abosheaishaa, Omar Nassar, Mostafa Alfishawy, Anthony Martinez   +3 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Awareness, Stigma, and Cultural Beliefs About Diabetes: A Qualitative Study of Somali Patients and Families

Diabetes, Metabolic Syndrome and Obesity
Abdifitah Abdullahi Mohamed,1 Mohamed Jayte,2 Farah Dubad Abdi,2 Ilhan Abdi,1 Abdikani Khalif3 1Department of Microbiology, Kampala International University, Kampala, Uganda; 2Department of Internal Medicine, Kampala International University, Kampala ...
Mohamed AA, Jayte M, Abdi FD, Abdi I, Khalif A   +4 more
doaj