Results 31 to 40 of about 1,115,329 (302)
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Tres circuitos migratorios Puebla-Estados Unidos: una lectura comparativa
Nuevo mundo - Mundos Nuevos, 2007 Nowadays, Mexican migration to the United States is characterized by its socio-demographic heterogeneity and multiethnic character; moreover, men and women join the migration circuits on the basis of their specific gender condition.
Maria Eugenia D’Aubeterre Buznego +1 more
doaj +1 more source
Internal Migration to the Gauteng Province [PDF]
, 2004 Gauteng, South Africa's economic powerhouse, has long been dependent on immigration to supply its labour requirements, a phenomenon deeply rooted in the province's early economic history and the development of mining and heavy industry.
Oosthuizen, Morne, Naidoo, Pranushka
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Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Internal Migration and Regional Population Dynamics in Europe: Spain Case Study [PDF]
, 2000 Internal migration has been a key component in Spain’s sub-national population dynamics over the last century, particularly during the 1960s and 1970s, when the rural exodus was at its peak.
Coll, A.G., Stillwell, J.
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Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
ASSESSMENT OF INTERNAL LABOR MIGRATION ON THE SOCIO-ECONOMIC DEVELOPMENT OF REGIONS
Статистика и экономика, 2016 The author, based on a sample survey of internal labor migration assesses its impact on the socio-economic development of the Republic of Kalmykia. Despite the development of administrative sources of data on migration, much of the data can only be ...
Nina A. Eldyaeva, Ekaterina S. Kovanova
doaj +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Demographic Research, 2019 Background: We introduce and provide the first comprehensive comparative assessment of the Federal Reserve Bank of New York/Equifax Consumer Credit Panel (CCP) as a valuable and underutilized dataset for studying internal migration within the United ...
Jack DeWaard +2 more
doaj +1 more source
Internal Migration and Regional Population Dynamics in Europe: Switzerland Case Study [PDF]
, 2000 This paper reports on internal migration and regional population dynamics in Switzerland. It examines briefly the main population trends in the last century and then turns to more detailed examination of internal migration patterns and trends in three ...
Durham, H. +4 more
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