Results 41 to 50 of about 1,119,262 (309)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Internal Migration and Regional Population Dynamics in Europe: Spain Case Study [PDF]

, 2000
Internal migration has been a key component in Spain’s sub-national population dynamics over the last century, particularly during the 1960s and 1970s, when the rural exodus was at its peak.
Coll, A.G., Stillwell, J.
core  

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

ASSESSMENT OF INTERNAL LABOR MIGRATION ON THE SOCIO-ECONOMIC DEVELOPMENT OF REGIONS

Статистика и экономика, 2016
The author, based on a sample survey of internal labor migration assesses its impact on the socio-economic development of the Republic of Kalmykia. Despite the development of administrative sources of data on migration, much of the data can only be ...
Nina A. Eldyaeva, Ekaterina S. Kovanova
doaj   +1 more source

Internal Migration and Regional Population Dynamics in Europe: Switzerland Case Study [PDF]

, 2000
This paper reports on internal migration and regional population dynamics in Switzerland. It examines briefly the main population trends in the last century and then turns to more detailed examination of internal migration patterns and trends in three ...
Durham, H., Kupiszewski, M., Rees, P., Reichle, M., Schuler, M.   +4 more
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Internal migration in the United States: A comprehensive comparative assessment of the Consumer Credit Panel

Demographic Research, 2019
Background: We introduce and provide the first comprehensive comparative assessment of the Federal Reserve Bank of New York/Equifax Consumer Credit Panel (CCP) as a valuable and underutilized dataset for studying internal migration within the United ...
Jack DeWaard, Janna Johnson, Stephan Whitaker   +2 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

The effect of internal migration on regional growth in Italy: a dynamic spatial panel data analysis

Investigaciones Regionales - Journal of Regional Research
This study assesses the effect of internal migration on regional growth in Italy at the NUTS-3 level over the period 2002-2019. The composition of the internal migration flows of the working-age population in Italy during the sample period appears ...
Francesca Centofanti, Roberto Basile, Francesca Licari, Jacopo Pitari   +3 more
doaj   +1 more source

Reinventing US Internal Migration Studies in the Age of International Migration [PDF]

Population, Space and Place, 2011
ABSTRACTI argue that researchers have sidelined attention to issues raised by US internal migration as they shifted focus to the questions posed by the post‐1960s rise in US immigration. In this paper, I offer some reasons about why immigration has garnered more attention and why there needs to be greater consideration of US internal migration and its ...
openaire   +2 more sources