Results 31 to 40 of about 355,225 (263)
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
On the Economic Geography of International Migration [PDF]
The World Economy, 2015 AbstractWe exploit the bilateral and skill dimensions from recent data sets of international migration to test for the existence of Zipf's and Gibrat's laws in the context of aggregate and high‐skilled international immigration and emigration using graphical, parametric and non‐parametric analysis.
Ozden, Caglar, Parsons, Christopher
openaire +5 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Internal borders and migration in India* [PDF]
Journal of Economic Geography, 2017 Internal mobility is a critical component of economic growth and development, as it enables the reallocation of labor to more productive opportunities across sectors and regions. Using detailed district-to-district migration data from the 2001 Census of India, the paper highlights the role of state borders as significant impediments to internal ...
Zovanga L. Kone +5 more
openaire +4 more sources
ASSESSMENT OF INTERNAL LABOR MIGRATION ON THE SOCIO-ECONOMIC DEVELOPMENT OF REGIONS
Статистика и экономика, 2016 The author, based on a sample survey of internal labor migration assesses its impact on the socio-economic development of the Republic of Kalmykia. Despite the development of administrative sources of data on migration, much of the data can only be ...
Nina A. Eldyaeva, Ekaterina S. Kovanova
doaj +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
Religion and international migration
, 2021 This is a draft chapter/article. The final version is available in Kaya, Ayhan (2021). “Religion and International migration," In Jeffrey Haynes (ed.), Handbook on Religion and International Relations. Cheltenham: Edward Elgar: 156-170. The material cannot be used for any other purpose without further permission of the publisher, and is for private ...
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
The effect of internal migration on regional growth in Italy: a dynamic spatial panel data analysis
Investigaciones Regionales - Journal of Regional ResearchThis study assesses the effect of internal migration on regional growth in Italy at the NUTS-3 level over the period 2002-2019. The composition of the internal migration flows of the working-age population in Italy during the sample period appears ...
Francesca Centofanti +3 more
doaj +1 more source