Results 31 to 40 of about 1,549,061 (240)

FACTORS AFFECTING STUDENTS’ CONFIDENCE IN PUBLIC SPEAKING

open access: yesJournal of Languages and Language Teaching, 2018
The researcher aimed to find out an internal and external factors that affected students’ confidence in public speaking performance. The kind of this research was qualitative, this study is dealing with Miles and Huberman theory, the sample of this ...
Muhammad Arif Pratama
doaj  

Research on management capacity components of heads of territorial bodies of the Ministry of Internal Affairs of Russia

open access: yesПсихология и право, 2020
The key objective of the Ministry of Internal Affairs of the Russian Federation is law enforcement within the country. Therefore, studying the problems of improving the professional development of managerial personnel in the system of the Ministry of ...
Burtsev A.O., Dashko M.N., Efimkina N.V.
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Vibrations of Plate Strips with Internal Periodic Structure

open access: yesEngineering Transactions, 2015
In this note vibrations of thin periodic plate strips with periodically distributed systems of three concentrated masses are analysed. Results of the non-asymptotic tolerance model are compared to those by the exact discrete model.
Jakub MARCZAK, Jarosław JĘDRYSIAK
doaj   +1 more source

Biophysical approaches for studying viral entry

open access: yesFEBS Letters, EarlyView.
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

On consequences of the principle of stationary action for dissipative bodies

open access: yesArchives of Mechanics, 2012
The aim of this note is to show possible consequences of the principle of stationary action formulated for dissipative bodies. The material structure with internal state variables is considered for those bodies.
W. Kosiński, P. Perzyna
doaj   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

α‐Synuclein aggregation landscape from phase separation to neurotoxic intermediates

open access: yesFEBS Letters, EarlyView.
Alpha‐synuclein aggregation in Parkinson's disease involves a complex landscape of transient intermediates, including oligomers, fibrils and liquid–liquid phase separation (LLPS). A view is emerging in which LLPS maturation into solid‐like condensates may contribute to the formation of neurotoxic species.
Silvia Arino   +2 more
wiley   +1 more source

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