Results 81 to 90 of about 10,298,744 (311)
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Sourcing of Internal Auditing: An Empirical Study [PDF]
In recent years, the scope of internal auditing has broadened considerably, increasing the importance of internal auditing as part of the organization’s management control structure.
Kruis, A.M. +2 more
core
Molecular Oncology, EarlyView.Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach +9 more
wiley +1 more source
Spatial structure of internal tidal waves generated on weak topographies
, 2010 The generation of internal gravity waves by barotropic tidal flow passing over a two-dimensional topography is investigated. Rather than calculating the conversion of tidal energy, this study focuses on delineating the geometric characteristics of the ...
范平, Singh VP, Fan P
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Spinor Structure and Internal Symmetries [PDF]
International Journal of Theoretical Physics, 2015 Spinor structure and internal symmetries are considered within one theoretical framework based on the generalized spin and abstract Hilbert space. Complex momentum is understood as a generating kernel of the underlying spinor structure. It is shown that tensor products of biquaternion algebras are associated with the each irreducible representation of ...
openaire +3 more sources
A Neural Network Based Approach to Modelling the Internal Structure of Transiting Exoplanets [PDF]
, 2022 Characterising the composition and internal structure of transiting exoplanets is a problem of high interest in current exoplanetary science. Since the observable parameters of such planets are very scarce, it is not possible to fully constrain the ...
Egger, Jo Ann, Alibert, Yann
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source