Results 111 to 120 of about 4,129,225 (254)

Impacts of forced and internal climate variability on changes in convective environments over the eastern United States

open access: yesFrontiers in Climate
Hazards from convective weather pose a serious threat to the contiguous United States (CONUS) every year. Previous studies have examined how future projected changes in climate might impact the frequency and intensity of convective weather using ...
Megan E. Franke   +3 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

open access: yesFEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh   +2 more
wiley   +1 more source

Partitioning uncertainty in climate projections for the Murray Darling Basin using large ensembles

open access: yesEnvironmental Research Communications
The Murray Darling Basin (MDB) in southeast Australia is a highly managed system, aiming to deliver resilient and sustainable outcomes for communities, industries, and the environment that share the water in the basin.
Anjana Devanand   +6 more
doaj   +1 more source

Texas Lottery Commission Internal Audit: Follow-Up Review

open access: yes, 2012
Report detailing the Internal Audit Division's follow-up review of six previously conducted internal audits in order to determine whether management has taken actions to correct conditions noted in the prior audits or has accepted the risk of not taking ...
Texas Lottery Commission. Internal Audit Division.
core  

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Unveiling the Dominant Factors Controlling the Long‐Term Changes in Northwest Pacific Tropical Cyclone Intensification Rates

open access: yesGeophysical Research Letters
Tropical cyclones (TCs), especially intense TCs, pose serious threats to life and property particularly in the affected coastal regions. Understanding the factors determining the TC intensification rate (IR) remains a great challenge.
Kexin Song, Ruifen Zhan, Yuqing Wang
doaj   +1 more source

Texas Lottery Commission Internal Audit: Jackpot Estimation

open access: yes, 2010
Report detailing the Internal Audit Division's completed review of Jackpot Estimation Procedures, the purpose of which was to verify that jackpot estimates, and the resulting advertised amounts, are derived in accordance with commission policies and ...
Texas Lottery Commission. Internal Audit Division.
core  

Evaluating GenAI‐produced feedback on undergraduate bioscience essays against good higher education feedback practice

open access: yesFEBS Open Bio, EarlyView.
This pilot study investigates the potential of Generative AI to provide formative feedback to students. ChatGPT was prompted to provide feedback on Year 1 Bioscience essays, which were evaluated against established good feedback practices. GenAI‐authored feedback had useful elements, but was limited in scope. GenAI may have potential to provide instant,
Annabel Court   +3 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

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