Results 91 to 100 of about 1,550,292 (307)

Fluctuating thermal environments of shallow-water rocky reefs in the Gulf of California, Mexico. [PDF]

, 2019
As part of a broad-scale study of the biogeography of rocky reefs in the Gulf of California, Mexico (GOC), we collected a continuous 1-yr temperature time series at ~5 m water depth at 16 sites spanning 5° of latitude and ~700 km along the western ...
Galland, Grantly R, Hastings, Philip A, Leichter, James J   +2 more
core  

Can we identify non-stationary dynamics of trial-to-trial variability?" [PDF]

, 2014
Identifying sources of the apparent variability in non-stationary scenarios is a fundamental problem in many biological data analysis settings. For instance, neurophysiological responses to the same task often vary from each repetition of the same ...
Balaguer-Ballester, Emilio, Budka, Marcin, Tabas-Diaz, A.   +2 more
core   +3 more sources

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source

Quantifying the role of internal variability in the temperature we expect to observe in the coming decades

Environmental Research Letters, 2020
On short (15-year) to mid-term (30-year) time-scales how the Earth’s surface temperature evolves can be dominated by internal variability as demonstrated by the global-warming pause or ‘hiatus’.
Nicola Maher, Flavio Lehner, Jochem Marotzke   +2 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

IceCube Non-detection of GRBs: Constraints on the Fireball Properties

, 2012
The increasingly deep limit on the neutrino emission from gamma-ray bursts (GRBs) with IceCube observations has reached the level that could put useful constraints on the fireball properties.
Dai, Zi-Gao, He, Hao-Ning, Liu, Ruo-Yu, Murase, Kohta, Nagataki, Shigehiro, Wang, Xiang-Yu   +5 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Natural Variability and External Forcing Factors That Drive Surface Air Temperature Trends over East Asia

Atmosphere
Community Earth System Model-Large Ensemble (CESM-LE) simulations are used to partition the Surface Air Temperature (SAT) trends over East Asia into the contribution of external forcing factors and internal variability.
Debashis Nath, Reshmita Nath, Wen Chen
doaj   +1 more source

Physical controls of Southern Ocean deep‐convection variability in CMIP5 models and the Kiel Climate Model

Geophysical Research Letters, 2017
Global climate models exhibit large biases in the Southern Ocean. For example, in models Antarctic bottom water is formed mostly through open‐ocean deep convection rather than through shelf convection.
A. Reintges, T. Martin, M. Latif, W. Park   +3 more
doaj   +1 more source