Results 71 to 80 of about 4,129,225 (254)

The Value of Initial Condition Large Ensembles to Robust Adaptation Decision‐Making

Earth's Future, 2020
The origins of uncertainty in climate projections have major consequences for the scientific and policy decisions made in response to climate change.
Justin S. Mankin, Flavio Lehner, Sloan Coats, Karen A. McKinnon   +3 more
doaj   +1 more source

Internal Developments In Japan and Indonesia

, 1984
21,5 cm; 90 ...
Internal
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

Natural Variability and External Forcing Factors That Drive Surface Air Temperature Trends over East Asia

Atmosphere
Community Earth System Model-Large Ensemble (CESM-LE) simulations are used to partition the Surface Air Temperature (SAT) trends over East Asia into the contribution of external forcing factors and internal variability.
Debashis Nath, Reshmita Nath, Wen Chen
doaj   +1 more source

The role of internal variability and external forcing on southwestern Australian rainfall: prospects for very wet or dry years. [PDF]

Sci Rep, 2023
Rauniyar SP, Hope P, Power SB, Grose M, Jones D.   +4 more
europepmc   +1 more source

Consistently estimating internal climate variability from climate model simulations [PDF]

, 2017
This paper introduces and applies a new method to consistently estimate internal climate variability for all models within a multi-model ensemble.
Olonscheck, D., Dirk Notz, Notz, D., Dirk Olonscheck   +3 more
core   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Tropical internal atmospheric variability and ENSO

, 2007
The interactive ensemble coupling strategy has been developed specifically to determine how noise due to internal atmosphere dynamics impacts climate variability within context of coupled general circulation model (CGCM). In this study we investigate the
Ben P Kirtman, 예상욱
core   +1 more source