Results 51 to 60 of about 4,129,225 (254)

Combining in situ measurements and altimetry to estimate volume, heat and salt transport variability through the Faroe–Shetland Channel [PDF]

, 2013
From 1994 to 2011, instruments measuring ocean currents (Acoustic Doppler Current Profilers; ADCPs) have been moored on a section crossing the Faroe–Shetland Channel.
K. M. Larsen, B. Berx, S. Østerhus, Larsen, K. M., Berx, Barbara, Osterhus, S., Hansen, Bogi, Jochumsen, K., Sherwin, Toby, B. Hansen, Larsen, Karin Margretha, Berx, B., T. Sherwin, Hansen, B., Østerhus, Svein, K. Jochumsen, Jochumsen, Kerstin, Sherwin, T.   +17 more
core   +2 more sources

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Observed winds alone cannot explain recent Arctic warming and sea ice loss

Environmental Research: Climate
Since the 1980s, observations show the Arctic surface has warmed four times more than the global mean. Over the Arctic Ocean, this recent large warming is connected to sea ice loss.
Ash L Gilbert, Jennifer E Kay, Edward Blanchard-Wrigglesworth, David A Bailey, Marika M Holland, Alexandra Jahn, David P Schneider   +6 more
doaj   +1 more source

Converged ensemble simulations of climate: possible trends in total solar irradiance cannot explain global warming alone

Frontiers in Earth Science
We address the hypothetical question of whether an increasing total solar irradiance (TSI) trend, without anthropogenic contributions, could be sufficient to explain the ongoing global warming.
Gábor Drótos, Gábor Drótos, Mátyás Herein, Mátyás Herein, Mátyás Herein, Tímea Haszpra, Imre M. Jánosi, Imre M. Jánosi   +7 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Evidence that end-of-century emulation errors under overshoot remain largely within internal variability in an Earth system model

Environmental Research Letters
Overshoot emission scenarios, in which a warming threshold is temporarily exceeded before returning to lower temperatures, are becoming increasingly relevant in the face of insufficient reductions of greenhouse gas emissions.
Shahine Bouabid, Christopher B Womack, Noelle E Selin, Raffaele Ferrari   +3 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

A model study of decadal climate variability and predictability associated with the Atlantic meridional overturning circulation

, 2012
This study addresses the decadal variability and predictability of the Atlantic Meridional Overturning Circulation (AMOC), and associated key variables, in two IPCC-class climate models.
Persechino, Aurelie S.A.
core   +1 more source

Internal Variability Reshapes Externally Forced Trends in Marine Cold‐Air Outbreak Frequency Over the Northern Hemisphere

Geophysical Research Letters
Marine cold‐air outbreaks (MCAOs) are key conduits of polar‐to‐midlatitude air‐mass exchange, strongly modulating wintertime air–sea heat fluxes, storm‐track activity, and the development of extreme cold conditions over adjacent continents.
Huanhuan Ran, Hainan Gong, Yulan Li, Kangjie Ma, Lin Wang   +4 more
doaj   +1 more source

US Climate Variability & Predictability Program Science Plan

, 2013
This report discusses the strategic scientific plan for the United States Climate Variability & Predictability ...
U.S. Climate Variability & Predictability Program. Scientific Steering Committee.
core