Results 31 to 40 of about 1,550,292 (307)

Tropical Pacific spatial trend patterns in observed sea level: internal variability and/or anthropogenic signature? [PDF]

open access: yes, 2012
In this study we focus on the sea level trend pattern observed by satellite altimetry in the tropical Pacific over the 1993–2009 time span (i.e. 17 yr).
Becker, M.   +4 more
core   +5 more sources

Stability of Intercelular Exchange of Biochemical Substances Affected by Variability of Environmental Parameters

open access: yes, 2010
Communication between cells is realized by exchange of biochemical substances. Due to internal organization of living systems and variability of external parameters, the exchange is heavily influenced by perturbations of various parameters at almost all ...
ANJA MIHAILOVIĆ   +8 more
core   +1 more source

UK emergency preparedness: a holistic local response? [PDF]

open access: yes, 2008
Purpose – This paper aims to argue that to address the consequences of climate change and variability a greater focus on pre-emergency planning that engages a wider stakeholder group must be adopted.
O'Brien, Geoff
core   +1 more source

The influence of internal climate variability on heatwave frequency trends

open access: yesEnvironmental Research Letters, 2017
Understanding what drives changes in heatwaves is imperative for all systems impacted by extreme heat. We examine short- (13 yr) and long-term (56 yr) heatwave frequency trends in a 21‐member ensemble of a global climate model (Community Earth System ...
S E Perkins-Kirkpatrick   +3 more
doaj   +1 more source

The vertical structure of upper ocean variability at the Porcupine Abyssal Plain during 2012-2013 [PDF]

open access: yes, 2016
This study presents the characterization of variability in temperature, salinity and oxygen concentration, including the vertical structure of the variability, in the upper 1000m of the ocean over a full year in the northeast Atlantic.
Binetti, Umberto   +4 more
core   +2 more sources

Temporal Decomposition Studies of GRB Lightcurves

open access: yes, 2013
Gamma-ray bursts (GRB) are extremely energetic events and produce highly diverse light curves. Light curves are believed to be resulting from internal shocks reflecting the activities of the GRB central engine.
Bhat, Narayana P.
core   +1 more source

Pacific Ocean Forcing and Atmospheric Variability are the Dominant Causes of Spatially Widespread Droughts in the Contiguous United States [PDF]

open access: yes, 2019
The contributions of oceanic and atmospheric variability to spatially widespread summer droughts in the contiguous United States (hereafter, pan-CONUS droughts) are investigated using 16-member ensembles of the Community Climate Model version 3 (CCM3 ...
Baek, Seung H.   +4 more
core   +2 more sources

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács   +8 more
wiley   +1 more source

Governance factors affecting internal auditors' ethical decision making: an exploratory study [PDF]

open access: yes, 2007
Purpose This paper explores the ethical decision making of internal auditors and the impact of corporate governance mechanisms thereon. It also explores whether ethical decision making is influenced by years of experience in internal auditing.
O'Leary, Conor, Stewart, Jenny
core   +2 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul   +13 more
wiley   +1 more source

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