Results 81 to 90 of about 3,017,924 (297)

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

open access: yesFEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey   +4 more
wiley   +1 more source

Interactions Between Nonlinear Internal Ocean Waves and the Atmosphere

open access: yesGeophysical Research Letters, 2019
The heterogeneity in surface roughness caused by transient, nonlinear internal ocean waves is readily observed in coastal waters. However, the quantifiable impact this heterogeneity has on the marine atmospheric surface layer has not been documented.
David G. Ortiz‐Suslow   +8 more
doaj   +1 more source

Recent insights into the molecular mechanism of ubiquinol oxidation by cytochrome bc1

open access: yesFEBS Open Bio, EarlyView.
The review reflects on the mechanism of the catalytic reaction in cytochrome bc1: the electron bifurcation that involves the separation of two electrons derived from the quinol oxidation to opposite sides of the enzyme across the membrane. This review summarizes the long‐standing effort to understand the mechanism of quinol oxidation catalyzed by ...
Anna Wójcik‐Augustyn   +2 more
wiley   +1 more source

Texas Lottery Commission Internal Audit: Retailer Accounts

open access: yes, 2009
Report detailing the Internal Audit Division's review of Retailer Accounts, in order to evaluate the adequacy and effectiveness of internal controls for ensuring accurate and efficient retailer collections and adjustments, and to evaluate tools in place ...
Texas Lottery Commission. Internal Audit Division.
core  

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

open access: yesFEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Geothermal waters of East-Ciscausasian artesian basin: economical aspects of using by the example of Khankala deposit

open access: yesИзвестия Томского политехнического университета: Инжиниринг георесурсов, 2017
The relevance of the discussed issue is caused by the growing interest in renewable energy, where geothermal waters have special significance. The prospects for using geothermal waters are proved by their environmental benefits.
Anvar Mansurovich Farkhutdinov   +6 more
doaj   +2 more sources

Analysis of internal wave in the Buru Island coastal waters, Banda Sea, Indonesia

open access: yesKuwait Journal of Science
The Indonesian throughflow (ITF) in the eastern part of Indonesia passes through the Maluku, Taliabu, Sula, and Buru Islands to the Banda Sea. The average depth of the Buru and Sula Islands is between 1000 m and 5000 m, with a narrow gap (sill) located ...
Asmoro N.W., Pranowo W.S., Nurhidayat
doaj   +1 more source

Living and Working Beneath the Sea – Next Approach

open access: yesPolish Maritime Research, 2017
The idea of living beneath the sea is very new if compared with millennia of shipping activity. In fact, ocean surface was considered mainly as medium suitable for transport of persons and goods as well as aggression and robbery.
Rowiński Lech
doaj   +1 more source

Death certificate: John A Waters

open access: yes, 1918
This is a photograph of the death certificate for John A. Waters, deceased on 1918-10-17, filed with the Arkansas Department of Health by the Ruebel Funeral Home in Little Rock.Transcribed.
Ruebel Funeral Home (Little Rock, Ark.)
core  

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

open access: yesFEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao   +10 more
wiley   +1 more source

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