Results 101 to 110 of about 279,853 (249)
Functionalized Carbon Nanotubes in the Brain: Cellular Internalization and Neuroinflammatory Responses [PDF]
, 2013 The potential use of functionalized carbon nanotubes (f-CNTs) for drug and gene delivery to the central nervous system (CNS) and as neural substrates makes the understanding of their in vivo interactions with the neural tissue essential.
Maurizio Prato (444708) +62 more
core +2 more sources
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Daratumumab induces CD38 internalization and impairs myeloma cell adhesion
OncoImmunology, 2018 Daratumumab (Dara), a human immunoglobulin G1 kappa (IgG1κ) monoclonal anti-CD38 antibody, has been approved by the U.S. Food and Drug Administration for the treatment of relapsed multiple myeloma (MM) as a single agent as well as in combination with ...
Jayeeta Ghose +17 more
doaj +1 more source
Pour une systématisation du pronom ce devant la copule être en opposition aux pronoms il impersonnel et il personnel [PDF]
Studii de Lingvistica, 2020 Our study, which falls within the field of teaching French as a foreign language, is inspired by two seemingly contradictory observations. The first concerns a recurrent error of Italian learners, who use the third-person personal pronoun, where only ...
Jean-Pierre Seghi
doaj
, 2008 Coupling anticancer drugs to synthetic polymers is a promising approach to improve the efficacy and reduce the side effects of these drugs. The pH -activated polymer has been demonstrated to be a successful drug delivery vehicle system, whereas the ...
LAI, PING-SHAN;LOU, PEI-JEN;HUANG, MING-YI;YOUNG, TAI-HORNG;SHIEH, MING-JIUM +1 more
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Pathways of EGF receptor internalization.
, 2013 EGF receptor can be internalized via clathrin dependent endocytosis (CDE) and clathrin independent endocytosis (CIE). A) Schematic representation of EGF receptor internalization according to Schmidt-Glenewinkel et al. [21].
Yvonne Koch (499083) +4 more
core +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
Gold nanoparticles as physiological markers of urine internalization into urothelial cells in vivo
, 2013 Samo Hudoklin,1 Daša Zupancic,1 Darko Makovec,2 Mateja Erdani Kreft,1 Rok Romih1 1Institute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia; 2Department for Materials Synthesis, Jozef Stefan Institute, Ljubljana,
Hudoklin S +4 more
core
Binding and internalization assay.
, 2014 (a) Luminescent signal after virus binding at various MOI. Increasing amounts of MHV-αN were bound to LR7ΔM15 cells on ice for 90 min before removing the inoculum and washing-off of unbound virus with ice-cold PBS.
Oliver Wicht (440906) +6 more
core +1 more source