Results 41 to 50 of about 2,888,152 (219)

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

The relationship of internalized weight bias to weight change in treatment-seeking overweight adults [PDF]

, 2011
Objective: The present study was designed to explore whether behavioral weight loss treatment is associated with changes in internalized weight bias among overweight and obese men and women.
Durso, Laura Elizabeth
core   +1 more source

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Testing the validity of the Norwegian translation of the modified weight bias internalization scale

Journal of Eating Disorders
Background Individuals with higher weight (overweight or obesity) may experience social stigma due to their weight. Weight stigma can be internalized with adverse health effects.
Tiffany Lussier, Jon Harald Quindao Tangen, Trine Tetlie Eik-Nes, Håvard R. Karlsen, Kjersti Hognes Berg, Charlotte Fiskum   +5 more
doaj   +1 more source

Nitride MXenes Beyond Carbides: Bridging the Gap Between Computational Prediction and Experimental Realization

Advanced Functional Materials, EarlyView.
Nitride MXenes remain constrained by a persistent gap between computational prediction and experimental realization. This Review identifies the thermodynamic, kinetic, and chemical barriers limiting their synthesis, critically evaluates emerging fabrication routes, and proposes a multidimensional computational‐experimental framework to accelerate the ...
Naresh Varnakavi, Masoud Soroush
wiley   +1 more source

Internalized weight-bias: psychological correlates and the role of social support among individuals seeking bariatric surgery

, 2022
An important factor to consider when examining the increased rates of mental illness among individuals seeking bariatric surgery is internalized weight bias. Internalized weight bias has been observed to be positively associated with depression, anxiety,
Scurrey, Samantha
core   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Anisotropic Masked Mycobacterium Potentiates Amplified Antitumor Trained Immunity via Spleen Targeting and Myelopoiesis Conversion

Advanced Materials, EarlyView.
An engineered Trojan Mycobacterium, developed via a “peeling‐off and masking‐up” strategy, functions as a powerful splenic myelopoiesis converter. This spleen‐targeted nanomedicine induces trained immunity to reprogram immunosuppressive myeloid reservoirs into antitumoral effectors.
Jin‐Ho Choi, Sang Nam Lee, Jang Hun Heo, Soyoung Park, Sei Hyun Park, Yong Taik Lim   +5 more
wiley   +1 more source

Obesity‐Related Beliefs, Concerns, and Stigmatizing Perceptions Among Adults Living With Obesity

Obesity Science & Practice
Background Weight stigma represents a barrier to effective obesity management and to achieving health equity. Although most research has focused on high‐income countries, data from Latin America remain scarce.
Luiz F. Viola, Cynthia M. Valerio, Raquel B. G. Muniz, Roberta M. C. Moreira Allgayer, Thaisa D. G. Trujilho, Alexandre Hohl, Rodrigo N. Lamounier, Maria Augusta Bernardini, Roberta Brito, Bruno Halpern, Fábio R. Trujilho   +10 more
doaj   +1 more source

Agreement with weight-neutral compared to weight-centric physical activity messages and relationships to sedentary behavior, physical activity, and internalized weight bias in people living in larger bodies

Health Literacy and Communication Open
Background Many anti-obesity health promotion campaigns focus on physical activity as a means to lose weight. Organizations have created positive images of people living with obesity being physically active with the intention of normalizing people in ...
Tanya R. Berry, Maxine M. Myre
doaj   +1 more source