Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins +3 more
wiley +1 more source
Impact of equivalent units of production on state-controlled unit cost calculation for fair pricing of pharmaceuticals: a scoping review. [PDF]
Udoh S, Wnuk-Pel T.
europepmc +1 more source
Ti6Al4V‐Bioglass‐Copper Composites for Load‐Bearing Implants
We have designed and manufactured a novel Ti64‐based composite by adding 45S5 bioglass (BG) and copper (Cu). Adding BG on titanium improves wear resistance and biocompatibility, whereas Cu addition improves mechanical strength while providing inherent lifelong bacterial resistance.
Lochan Upadhayay +3 more
wiley +1 more source
Establishing an independent HTA agency in Ukraine: a conceptual framework for governance, operations, and long-term sustainability. [PDF]
Sucu R, Erku D, Filiniuk O, Kohler R.
europepmc +1 more source
Isolation Defines Identity: Functional Consequences of Extracellular Vesicle Purification Strategies
Four extracellular vesicle purification strategies are compared using ovarian‐cancer ascites and ES‐2 cell supernatants. A novel workflow links purification to function by combining particle‐normalized proteomics with matched cell‐free and cell‐based assays.
Christian Preußer +10 more
wiley +1 more source
PEP-Hep: A cluster randomised controlled trial of a prison education programme to improve hepatitis B and C testing uptake and treatment initiation in Ghana - A study protocol. [PDF]
Senoo-Dogbey VE +8 more
europepmc +1 more source
A multilayered small‐caliber vascular scaffold combining electrospinning and 4‐axis printing is developed and biofunctionalized with marine sulfated polysaccharides from Holothuria tubulosa. The resulting construct exhibits enhanced hemocompatibility, tunable mechanical properties, and supports endothelial and smooth muscle cell adhesion and ...
Gabriele Obino +9 more
wiley +1 more source
Binding Multilateral Framework for South Asian Air Pollution Control: An Urgent Call for SAARC-UN Cooperation. [PDF]
Sriram S, Adhikari S.
europepmc +1 more source
Regional carbon emission reduction potential estimation based on scenario analysis under emission standards. [PDF]
Xia X, Yan Z, Zhang S, Zhu D.
europepmc +1 more source
Prenatal therapies: a Points to Consider framework for responsible innovation. [PDF]
Meslin EM +3 more
europepmc +1 more source

