Results 121 to 130 of about 49,240 (244)

The In Vitro Transgenic Rodent Assay in Primary MutaMouse Hepatocytes Compared to the Mammalian Cell Gene Mutation Assay Using the HPRT Gene

Environmental and Molecular Mutagenesis, EarlyView.
ABSTRACT Gene mutations can be detected in mammalian cells in vitro using indicator genes such as the hypoxanthine‐guanine‐phosphoribosyltransferase (HPRT) gene. These assays have been adopted as OECD test guidelines (TG, e.g., OECD TG no. 476) and are used for regulatory purposes.
Alina Göpfert, Kylee Kendra Marie Ronnenberg, Claudia Ruelker, Silke Spang, Naveed Honarvar, Robert Landsiedel   +5 more
wiley   +1 more source

Review of National and International Accreditation of Pharmacy Programs in the Gulf Cooperation Council Countries. [PDF]

Am J Pharm Educ, 2018
Alkhateeb FM, Arkle S, McDonough SLK, Latif DA.   +3 more
europepmc   +1 more source

Building the Plane While Flying It: How Projects Serve to Implement, Pilot and Co‐Create EU Policy

European Policy Analysis, EarlyView.
ABSTRACT This article theorizes how projectified governance enables bottom‐up policy shaping in the EU, using the European Universities Initiative (EUI) as a case study. It develops a framework that combines bottom‐up Europeanization with resource exchange theory to explain how project networks influence EU policymaking.
Alina Felder‐Stindt
wiley   +1 more source

Targeting Hsp90 with cemdomespib reduces seizure burden and alters disease course in preclinical epilepsy models

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a chronic neurological disorder characterized by recurrent seizures and frequent cognitive and psychiatric comorbidities. Although current antiseizure medications provide symptomatic relief, they fail to prevent or modify epileptogenesis.
Yara Sheeni, Prince Kumar Singh, Sereen Sandouka, Taige Zhang, Alina Nemirovski, Aseel Saadi, Rhoda Olowe Taiwo, Matthew C. Walker, Tawfeeq Shekh‐Ahmad   +8 more
wiley   +1 more source

An algorithm for seizure detection in rodents

Epilepsia Open, EarlyView.
Abstract Objective Epilepsy animal research often relies on long‐term intracranial electroencephalographic (iEEG) recordings. Here, we describe an artificial neural network (ANN) algorithm for automatic detection of seizures. Methods The algorithm was trained on iEEG recordings of three mouse models of chronic epilepsy: (1) the pilocarpine model of ...
Lyna Kamintsky, Gerben van Hameren, Itai Weissberg, Pooyan Moradi, Ofer Prager, Alaa Abu Ahmad, Lior Schori, Albert Becker, Yaniv Zigel, Alon Friedman   +9 more
wiley   +1 more source

International accreditation in Iranian universities of medical sciences: a qualitative analysis of challenges and solutions. [PDF]

BMC Med Educ
Hashjin AA, Shabani E, Tahmasebi A, Farrokhi P, Seval Akgün H.   +4 more
europepmc   +1 more source

Shortened cataract surgery by standardisation of the perioperative protocol according to the Joint Commission International accreditation: a retrospective observational study. [PDF]

BMJ Open, 2019
Okumura Y, Inomata T, Iwagami M, Eguchi A, Mizuno J, Shiang T, Kawasaki S, Shimada A, Inada E, Amano A, Murakami A.   +10 more
europepmc   +1 more source

The multiple hit model of infantile and epileptic spasms: The 2025 update

Epilepsia Open, EarlyView.
Abstract Objective Infantile and epileptic spasms syndrome (IESS) is a developmental and epileptic encephalopathy manifesting with epileptic spasms and poor neurodevelopmental outcomes. There is an urgent need for the development of more effective and tolerated therapies.
Aristea S. Galanopoulou, Wenzhu B. Mowrey, Wei Liu, Anna Maria Katsarou, Qianyun Li, Oleksii Shandra, Solomon L. Moshé   +6 more
wiley   +1 more source

International accreditation for acute stroke care: lessons learnt from a Kenyan Stroke Centre. [PDF]

Front Stroke
Sokhi DS.
europepmc   +1 more source

The impact of Joint Commission International accreditation on time periods in the operating room: A retrospective observational study. [PDF]

PLoS One, 2018
Inomata T, Mizuno J, Iwagami M, Kawasaki S, Shimada A, Inada E, Shiang T, Amano A.   +7 more
europepmc   +1 more source