Results 41 to 50 of about 49,240 (244)

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Comparison of Hospital Accreditation Standards in Selected Worlds: A Comparative Review [PDF]

Journal of Evidence Based Health Policy, Management & Economics
Background: Accreditation of hospitals plays a significant role in increasing the safety, quality and effectiveness of medical services and increasing the efficiency of hospitals.
Akbar Rasouli, Abasat Mirzaei, Taher Maleki, Sanaz Zeydabadi   +3 more
doaj  

A prospective, multi-method, multi-disciplinary, multi-level, collaborative, social-organisational design for researching health sector accreditation [LP0560737]

BMC Health Services Research, 2006
Background Accreditation has become ubiquitous across the international health care landscape. Award of full accreditation status in health care is viewed, as it is in other sectors, as a valid indicator of high quality organisational performance ...
Braithwaite Jeffrey, Westbrook Johanna, Pawsey Marjorie, Greenfield David, Naylor Justine, Iedema Rick, Runciman Bill, Redman Sally, Jorm Christine, Robinson Maureen, Nathan Sally, Gibberd Robert   +11 more
doaj   +1 more source

All‐PEG‐Like Block Copolymers Self‐Assemble into Stealth Nanocarriers for Drug Delivery

Advanced Science, EarlyView.
Self‐assembling nanoparticles composed entirely of POEGMA are engineered by exploiting side‐chain–dependent amphiphilicity and tunable thermoresponsive behavior. These single‐material nanocarriers encapsulate diverse hydrophobic drugs with high efficiency, retain therapeutic activity, improve in vivo efficacy, and evade anti‐PEG antibodies.
Parul Sirohi, Brooke E. Silverstein, Yulia Shmidov, Sonal Deshpande, Joy Tong, Yvonne Y. Ma, Chinmay S. Potnis, Soumen Saha, Xinghai Li, Max R. Ney, Sarah Y. Kim, Joshua J. Milligan, Lixin Fan, Matthew L. Becker, Daniel Reker, Ashutosh Chilkoti   +15 more
wiley   +1 more source

Mozambique’s journey toward accreditation of the National Tuberculosis Reference Laboratory

African Journal of Laboratory Medicine, 2017
Background: Internationally-accredited laboratories are recognised for their superior test reliability, operational performance, quality management and competence.
Sofia O. Viegas, Khalide Azam, Carla Madeira, Carmen Aguiar, Carolina Dolores, Ana P. Mandlaze, Patrina Chongo, Jessina Masamha, Daniela M. Cirillo, Ilesh V. Jani, Eduardo S. Gudo   +10 more
doaj   +1 more source

miR‐135a‐5p Is a Promising Target to Prevent the Glomerulosclerosis Associated with Podocyte Developmental Toxicity in Offspring Induced by Prenatal Dexamethasone Exposure

Advanced Science, EarlyView.
Prenatal dexamethasone exposure (PDE) programs persistent podocyte developmental injury and adult glomerulosclerosis. Mechanistically, glucocorticoid receptor (GR) binds the miR‐135a‐5p promoter and recruits the histone acetyltransferase p300, increasing promoter histone acetylation and sustaining miR‐135a‐5p expression. Elevated miR‐135a‐5p suppresses
Xiaoqi Zhao, Haiyun Chen, Yanan Zhu, Zhiping Xia, Hangyuan He, Yutang Liu, Tianshu Yang, Hui Wang, Ying Ao   +8 more
wiley   +1 more source

How Iran’s Hospital Accreditation Program Meets the International Society for Quality in Health Care(ISQua)

Health Technology Assessment in Action
Background: Hospital health service quality is a fundamental component of the health system. Hospital accreditation is a key approach to enhancing this quality, necessitating the correct implementation of processes.
Lida Shams, Farid Gharibi, Tahmineh Poursaki, Ali Maher   +3 more
doaj   +1 more source

ISO 15189 accreditation: Navigation between quality management and patient safety [PDF]

Journal of Medical Biochemistry, 2017
Accreditation is a valuable resource for clinical laboratories and the development of an International Standard for their accreditation represented a milestone on the path towards improved quality and safety in laboratory medicine. The recent revision of
Plebani Mario, Sciacovelli Laura
doaj  

Proposal for a graded approach to disclosure of interests in accredited CME/CPD [PDF]

Journal of European CME, 2015
Disclosing conflicts of interest (COIs) is an important step in the management of COIs and is considered to be crucial to the trustworthiness of presenters. There are significant variations in disclosure procedures regarding the following:a.
Reinhard Griebenow, Craig Campbell, Amir Qaseem, Sean Hayes, Jennifer Gordon, Lampros Michalis, Heinz Weber, Eugene Pozniak, Robert Schäfer   +8 more
doaj   +1 more source

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source