Results 51 to 60 of about 172,418,878 (260)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Type 2 segmental glomangioma - Case report [PDF]

Anais Brasileiros de Dermatologia, 2015
Glomus tumors originate from modified perivascular muscle cells. The most common form is the solitary one. The multiple form may be associated with dominant genetic inheritance.
Camila Raposo Cabral, Jayme de Oliveira Filho, Julliene Lika Matsumoto, Stela Cignachi, Ana Carolina Franco Tebet, Kássila da Rosa Nasser   +5 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

International Classification of Diseases (ICD) medications and procedural codes.

, 2022
International Classification of Diseases (ICD) medications and procedural codes.
Xiaohui Jiang (810650), Jun Su (53405), Melitza Iglesias-Rodriguez (9358452), Cara L. Frankenfeld (14266012), Parija Patel (14266015), Catherine M. Broome (14266009), Naushin Hooda (11180081), Gina Nicholson (8304429), Jon Fryzek (2601550)   +8 more
core   +1 more source

Dissociative disorders: Reinvention or reconceptualization of the concept?

Indian Journal of Social Psychiatry, 2018
“Dissociative disorders” have existed since antiquity, but the concept has undergone major transformations over time. The presence of different theoretical explanations; lack of consensus regarding nosological status; inconclusive evidence with respect ...
Nidhi Malhotra, Nitin Gupta
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Report of the United States Delegation to the International Conference for the Eighth Revision of the International Classification of Diseases, Geneva, Switzerland, July 6-12, 1965 [PDF]

Discussion and recommendations at the Conference that was concerned primarily with Eighth Revision of the International Classification of Diseases and gave some consideration to multiple-cause tabulation and analysis and to hospital statistics ...

core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Estimate of selected comparability of ratios dased on dual coding of 1976 death certificates by the eighth and ninth revisions of the International Classification of Diseases [PDF]

One of the efforts to maintain the tradition of progress in the classification of diseases has Izccn the practice, begun in 1900, to revise about every 10 years what is now the International Classification of Diseases (ICD).

core  

High-quality Disease Classification in Line with International Standards: Current Status and Reflections

Xiehe Yixue Zazhi
With the widespread adoption of the International Classification of Diseases (ICD) in China's medical evaluation and healthcare payment systems, the importance of disease classification coding has become increasingly prominent, drawing considerable ...
ZHOU Jiong, LIU Aimin
doaj   +1 more source