Results 121 to 130 of about 240,921 (262)

Master Regulator SMC1A, Stabilized by N6‐Methyladenosine Reader IGF2BP1, Promotes HCC Progression Through Facilitating Enhancer–Promoter Interaction of Nestin

Advanced Science, EarlyView.
IGF2BP1‐mediated m6A stabilization sustains SMC1A expression, enabling cohesin‐associated chromatin regulation of Nestin in hepatocellular carcinoma. This work reveals an epitranscriptomic‐chromatin‐cytoskeletal regulatory axis linked to malignant phenotypes and identifies SMC1A as a biologically relevant vulnerability in HCC.
Zhenxiang Peng, Diguang Wen, Lu Zeng, Lin Lv, Shengtao Liao, Wenguang Zhang, Zhechuan Mei, Chuanfei Li   +7 more
wiley   +1 more source

Ligand‐Defined Interfacial Chemistry Enables Instant and Sequence‐General DNA Chemisorption on Gold Nanoparticles Toward Label‐Free SERS With Single‐Base Resolution

Advanced Science, EarlyView.
Ascorbic Acid‐Engineered Interface Enables Universal DNA Functionalization on Gold Nanoparticles: Attenuating electrostatic repulsion and leveraging synergistic hydrogen‐bonding interactions significantly lowers the kinetic barrier for DNA adsorption, enabling rapid and sequence‐general functionalization of non‐thiolated DNA‐requiring only a single ...
Guangping Li, Cheng Wang, Xinyue Wu, Zhongxiang Ding, Heng Gao, Zhonggang Liu, Yu Zhang, Jinai Chen, Feng Wang, Honglin Liu   +9 more
wiley   +1 more source

International cooperation and the challenge of internet accessibility in Caribbean territories: example of a collaborative platform between the University Hospital of Martinique and Ramón González Coro Hospital in Cuba, through the French PRPH-3 program. [PDF]

BMC Med Educ, 2023
Houpert R, Almont T, Mésenge C, Kleinebreil L, Forlini L, Magnone B, Leroux V, Vestris M, Montabord C, Carmenate J, Galán Y, Rubio MC, Enriquez R, Burte C, Gatimel N, Bujan L, Kara N, Edwige O, Huyghe É, Joachim C, Véronique-Baudin J.   +20 more
europepmc   +1 more source

A Non‐Canonical Role of SMAD4 in Regulating 3D Genome Architecture to Inhibit Lung Squamous Cell Carcinoma Development

Advanced Science, EarlyView.
SMAD4 is identified as a guardian of 3D genome architecture in lung squamous cell carcinoma. Loss of SMAD4 unleashes EP300 at chromatin loop anchors, strengthening enhancer–promoter looping and H3K27ac at the SOX2 locus to drive aberrant SOX2 activation and tumor cell proliferation.
Qian Tang, Chen Lian, Xinyan Han, Xuhan Zhang, Zihan Wang, Boyu Wang, Taoyu Zhu, Xinrui Lin, Xiaolei Wang, Yaping Xu, Manyu Xiao, Zijin Wang, Junming Li, Silin Chen, Yunze Wang, Yufei Liu, Songsong Li, Zuolin Shen, Xi Lu, Xueqi Han, Yilu Zhou, Mingyang Xiao, Jiayi Ran, Xiaoran Cao, Xinyi Xu, Hugo Sámano‐Sánchez, Alfredo Rodríguez, Lian Wang, Shuifang Chen, Zhanyu Xu, Shirong Zhang, Nuo Yang, Yong Tang, Jian Liu   +33 more
wiley   +1 more source

Training young Russian physicians in Uganda–A unique program for introducing global health education in Russia

Annals of Global Health, 2014
B.A. Ziganshin, L.M. Yausheva, M. Sadigh, A. Pichugin, A. Ziganshin, A. Sozinov, M. Sadigh   +6 more
doaj   +1 more source

Orthopaedic Disorders in Cerebral Palsy in International Cooperation Projects: A Descriptive Cross-Sectional Study. [PDF]

Int J Environ Res Public Health, 2021
Garrido-Ardila EM, Caro-Puertolas B, Jiménez-Palomares M, Montanero-Fernández J, Rodríguez-Domínguez T, Rodríguez-Mansilla J.   +5 more
europepmc   +1 more source

Large Temperature‐invariant Anomalous Nernst Effect in Non‐collinear Antiferromagnet Mn3Pt

Advanced Science, EarlyView.
Based on the noncollinear antiferromagnetic Mn3Pt thin films, the composition‐tunable Mn‐3d orbital states directly govern the Berry curvature. As a result, a giant and temperature‐invariant anomalous Nernst coefficient of 0.71 µV/K is achieved under Mn‐rich conditions.
Pengwei Gong, Xiaolin Zhang, Wei Zhu, Mingzhi Wang, Chang Pan, Aoqi Xu, Yandong Guo, Yuheng Li, Jiaxin Chen, Yanchang Zhou, Zhong Shi, Dingfu Shao, Liang Liu, Shiming Zhou, Yicheng Guan, Ruiqing Cheng, Xuepeng Qiu   +16 more
wiley   +1 more source

First corpus callosotomy for medically refractory epilepsy in The Gambia: an international cooperation case report and historical review. [PDF]

Acta Epileptol
Gal ZT, Manneh EK, Gupta S, Luiselli GA, Cham M, Ceesay A, Nyassi M, Jobe Y, Oguocha R, Barry M, Gomez MF, Jammeh M, Bojang O, Jagne T, Jallow F, Njie A, Jallow CS, Bittaye M, Joof M, Marenah KS, Sanchez YC, Mbaye M, Doumbia N, Kangakan S, Sarpong P, Alkhateeb MA, Cobas ER, Janneh L, Rolston JD, Jabang JN.   +29 more
europepmc   +1 more source

COVID-19 in Central Asia: Uzbekistan's new approach to international cooperation. [PDF]

Lancet Reg Health Eur, 2021
Shadmanov A, Boklage E, Storozhenko O, Jansen A, COVID-19 mission team for Uzbekistan.   +4 more
europepmc   +1 more source

Unconventional Hysteretic Charge Filling in Moiré‐Reconstructed Helical Trilayer Graphene

Advanced Science, EarlyView.
In helical trilayer graphene, sequential twisting reconstructs the moiré landscape into periodic domains separated by aperiodic boundaries. Longitudinal transport reveals sweep‐direction‐dependent hysteresis, while the Hall response traces this behavior to hysteretic charge filling at the aperiodic boundaries.
Hangyeol Park, Junhyeok Oh, Rasoul Ghadimi, Chiranjit Mondal, Yungi Jeong, Won Beom Choi, Kenji Watanabe, Takashi Taniguchi, Bohm‐Jung Yang, Joonho Jang   +9 more
wiley   +1 more source