Results 141 to 150 of about 240,921 (262)

The impact of hepatitis B vaccination program in central Vietnam; evaluation by population-based, cross-sectional seroprevalence survey of HBsAg

open access: yesInternational Journal of Infectious Diseases, 2020
K. Komada   +3 more
doaj   +1 more source

Overcoming borders: International cooperation in re-use and re-interpretation of omics data in Fontan circulation. [PDF]

open access: yesInt J Cardiol Congenit Heart Dis
Michel M   +5 more
europepmc   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

open access: yesAdvanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao   +10 more
wiley   +1 more source

Mechanical Activation of Piezo1 Drives Osteoarthritis Through Kdm5c‐Mediated Epigenetic Silencing

open access: yesAdvanced Science, EarlyView.
Excessive mechanical stress activates Piezo1, triggering Ca2+‐dependent cytoskeletal forces that deform the nucleus and reduce H3K4me3. Kdm5c demethylates H3K4me3 at Col2a1 and Runx3 promoters. Kdm5c knockout rescues degradation. Repurposed telmisartan directly inhibits Kdm5c, blocking this axis and showing disease‐modifying efficacy in mouse OA models
Tianyou Kan   +13 more
wiley   +1 more source

[Telemedicine in developing countries and international cooperation]. [PDF]

open access: yesAten Primaria
Rossetti AF   +5 more
europepmc   +1 more source

TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain

open access: yesAdvanced Science, EarlyView.
TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando   +2 more
wiley   +1 more source

Thermoelectric Properties of a Diketopyrrolopyrrole Polymer With Radical Pending Units

open access: yesAdvanced Electronic Materials, EarlyView.
The successful incorporation of TEMPO radicals as side‐chain groups onto the conjugated backbone of an n‐type polymer significantly enhanced the doping efficiency of N‐DMBI via a hydrogen transfer doping mechanism. ABSTRACT Organic n‐type polymers usually suffer from relatively low electrical conductivity which hampers their application as an active ...
Jiang Jing   +16 more
wiley   +1 more source

The CIMMYT Australia ICARDA Germplasm Evaluation concept: a model for international cooperation and impact. [PDF]

open access: yesFront Plant Sci
Trethowan RM   +13 more
europepmc   +1 more source

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